DNA Test Flashcards
Polymers
Made of many repeating monomers
Monomers
Single unit
Base Pairing Rule (Char-gaff’s Rule)
Adenine always pairs with Thymine
Cytosine always pairs with Guanine
Helicase
Moves down DNA molecule and separates two strands of double helix, result is formation of two DNA template strands
DNA Polymerase
Forms covalent bonds b/w newly paired nucleotides
Free Floating DNA
In environment of DNA template strands
Available to form complementary strands pairs with nucleotides on template strand
Process of DNA Replication
Unwinding of double helix by Helicase and formation of two DNA template strands (Hydrogen bond breaks)
Addition of complementary nucleotides and covalent bonding by DNA polymerase
Aug
Met (Start)
Central Dogma of Biology
Two step process, transcription & translation, which information in genes flows into protein
DNA —> RNA —> Protein
Genetic Code
Set of rules by which information within genetic material such as DNA is translated into protein by living cells
Determines everything about a person
AUG-start codon
64 triplets of nucleotides
Translation for Reading
Position corresponds with order of letters
Relationship
3 nucleotides = 1 codon
1 amino acid = 1 codon
Missense Mutation
Leads to amino acid change
Nonsense Mutation
Causes premature STOP codon before protein is complete
Frameshift Mutation
(Insertion/deletion/duplication) Changes frame reading, alters protein