DNA Synthesis and Repair Flashcards

1
Q

Gene

A

Small, specific protein

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2
Q

What happens to the telomere or buffer zone

A

Gets cut off every time DNA gets copied

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3
Q

Telomerase (enzyme) does what?

A

Lengthen telomere back to original length

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4
Q

Overview of DNA Replication

A

Strand of DNA is pulled apart to make a new strand resulting in 2 strands

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5
Q

What has to be placed for DNA to be placed during replication?

A

RNA primer called primase

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6
Q

What does halicase do?

A

Break or pull apart strands of DNA

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7
Q

What does topoisomerase do?

A

Makes sure the strand of DNA doesn’t get tangled

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8
Q

What places the new DNA?

A

DNA polymerase 3

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9
Q

How is DNA read?

How is DA laid down?

A

Read 3’ to 5’

Laid 5’ to 3’

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10
Q

Where is the ‘leading strand’?

A

Moving towards the fork

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11
Q

What are okolzaki fragments?

A

Form the lagging end

Move away from the fork

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12
Q

What replaced the RNA primer (primase)?

A

DNA polymerase I

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13
Q

What is ligase?

A

Glue that connects DNA fragments

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14
Q

How many leading and lagging strands are there? How much new DNA is there?

A

2 leading, 2 lagging

4 new DNA

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15
Q

What is the origin of replication?

A

Where DNA replication begins

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16
Q

Why does DNA proof-read?

A

Sometimes there are mispairs

17
Q

What happens when proof-reading doesn’t work?

A

It is replicated

18
Q

What happens in mismatch repair?

A

Enzymes recognize mismatch and remove it to replace it with the correct sequence nucleotide