DNA Structure and Function Flashcards
Where was DNA isolated from?
White blood cells
What does adenine pair with?
Thymine
What forms the backbone of a DNA?
Alternating deoxyribose sugars and phosphates
What ave the components of the nucleotides?
Nitrogenous base, phosphate, group 5 carbon sugar
What are the nitrogenous bases?
Purines: adenine and guanine
Pyrimidines: cytosine, thymine and uracil
What pairs with thymine?
Adenine
What pairs with guanine?
Cytosine
What pairs with cytosine?
Guanine
What pairs with guanine in RNA?
Uracil
What is the structure of purines?
Double ring structure with a six member ring fused to a five membered ring
What is the structure of pyrimidines?
Smelled in size and have a six membered ring structure
How many hydrogen bonds connect adenine and thymine
2 hydrogen bonds
How many hydrogen bonds connect cytosine and guanine?
3 hydrogen bonds
Describe how the bases are arranged in the ladder model of DNA?
- Adenine pairs with thymine and forms 2 hydrogen bonds
- cytosine pairs with guanine and forms 3 hydrogen bonds
- backbone is formed by alternating sugar deoxyribose and phosphate group
Where does DNA and RNA occur in eukaryotic cells?
Separate compartments from protein synthesis
Where does DNA and RNA occur in prokaryote cells?
Occur together
What is conservative in DNA replication?
DNA molecule would get copied and make a new second complete molecule
What is semi-conservative in DNA replication?
Each DNA strand separates and serves as a template for a new strand
What is dispersive in DNA replication?
DNA molecule would get cut into pieces and then after being copied, these pieces would be incorporated into two new DNA molecules
What does DNA polymerase do in prokaryotes for DNA replication?
Adds nucleotides one by one to the growling DNA chain
What does DNA pol l do in prokaryotes for DNA replication?
Important accessory enzyme in DNA replication
What does DNA pol ll do in prokaryotes for DNA replication?
Primarily required for repair
What does DNA pol lll do in prokaryotes for DNA replication?
Enzyme required for DNA synthesis
What is the DNA replication process?
- DNA double helix unwinds, separating into 2 strands (unwinding)
- Each strand serves as a template (pairing)
- DNA polymerases link with nucleotides together to form new strands (joining)
- 2 strands twist back into double helix ( rewinding)