DNA Structure Flashcards

1
Q

Define the term “Eukaryotes”.

A

Eukaryotes are organisms made up of cells that possess a membrane-bound nucleus that holds genetic material as well as membrane-bound organelles.

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2
Q

Define the term “nucleus”.

A

A nucleus is a membrane-bound organelle that contains the cell’s chromosomes (genetic material). Pores in the nuclear membrane allow for the passage of molecules in and out of the nucleus.

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3
Q

Define the term “membrane”.

A

A membrane is the thin layer that forms the outer boundary of a living cell or of an internal cell compartment. The outer boundary is the plasma membrane, and the compartments enclosed by internal membranes are called organelles.

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4
Q

Define the term “organelle”.

A

An organelle is a subcellular structure that has one or more specific jobs to perform in the cell, much like an organ does in the body.

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5
Q

Define the term “nuclear pore”.

A

The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm.
Each nuclear pore is a large complex of proteins that allows small molecules and ions to freely pass, or diffuse, into or out of the nucleus.

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6
Q

Define the term “nucleoplasm”.

A

The nucleoplasm; (also known as karyoplasm, karyolymph or nucleus sap); is a type of protoplasm, and is enveloped by the nuclear envelope/membrane.
The nucleoplasm includes the chromosomes and nucleolus.

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7
Q

Define the term “metabolism”.

A

Metabolism is the sum of the chemical reactions that take place within each cell of a living organism and that provide energy for vital processes and for synthesizing new organic material.

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8
Q

Define the term “nucleolus”.

A

The nucleolus is the distinct structure present in the nucleus of eukaryotic cells. Primarily, it participates in assembling the ribosomes, alteration of transfer RNA and sensing cellular stress. The nucleolus is composed of RNA and proteins, which form around specific chromosomal regions

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9
Q

Define the term “chromatin network”.

A

Chromatin is a mass of genetic material composed of DNA and proteins that condense to form chromosomes during eukaryotic cell division. The chromatin is the network of the cell nucleus, which contains all the DNA of the nucleus of the cell.

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10
Q

Define the term “DNA”.

A

Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.

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11
Q

Define the term “chromosome”.

A

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA).

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12
Q

Define the term “mitochondria”.

A

Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell’s biochemical reactions.

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13
Q

Define the term “chloroplast”.

A

Chloroplasts are plant cell organelles that convert light energy into relatively stable chemical energy via the photosynthetic process. Chloroplasts also provide diverse metabolic activities for plant cells (e.g. fatty acid synthesis)

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14
Q

Define the term “extranuclear DNA”.

A

Extranuclear DNA are the DNA molecules that are present outside the nucleus in the cytoplasm. The mitochondria have a circular DNA known as mt-DNA and chloroplast has Ct-DNA. This DNA is the site of extranuclear chromosomes. These chromosomes are responsible for the inheritance of extrachromosomal characters

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15
Q

Define the term “RNA”.

A
Ribonucleic acid (RNA) is one of the three major biological macromolecules that are essential for all known forms of life.
The primary role of RNA is to convert the information stored in DNA into proteins.
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16
Q

Define the term “monomers”.

A

Monomers are the smaller units from which larger molecules are made.
Monosaccharides, amino acids and nucleotides are examples of monomers.

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17
Q

Define the term “nucleotides”.

A

A nucleotide is the basic building block of nucleic acids.
A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base.

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18
Q

Define the term “cytoplasm”.

A

Cytoplasm is a viscous solution that fills each cell, suspends the organelles within the cell and is enclosed by the cell membrane.
It is mainly composed of water, salts, and proteins.

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19
Q

Define the term “hypothesis”.

A

A hypothesis is a suggested solution for an unexplained occurrence that does not fit into current accepted scientific theory.

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20
Q

Define the term “x-ray”.

A

X-rays are a form of electromagnetic radiation that can be used for medical imaging.

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21
Q

Define the term “helix”.

A

A helix is a shape like a corkscrew or spiral staircase.

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22
Q

Define the term “model”.

A

A physical, mathematical, or otherwise logical representation of a system, entity, phenomenon, or process.

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23
Q

What is the Nobel Prize?

A

The Nobel Prizes are prizes awarded annually by Swedish academies and Norwegian committees to individuals and organizations who make outstanding contributions in the fields of chemistry, physics, literature, peace, and physiology or medicine. est. 1895.

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24
Q

What is a Meccano-like model?

A

A Meccano-like model is perhaps the most famous in modern science; consisting of metal plates bolted together in a spiral.

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25
Q

What is a polymer?

A

A polymer is a substance that is built from a large number of smaller units (subunits) bonded together.

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26
Q

What is a monomer?

A

A monomer is a molecule that can react with other molecules to form much larger molecules (polymers).

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27
Q

What are nucleotides and what do they consist of?

A

Nucleotides are the basic structural unit of nucleic acids such as DNA. They consist of a sugar molecule attached to a phosphate group and a nitrogenous base.

28
Q

What is deoxyribose sugar?

A

Deoxyribose sugar is a 5-carbon monosaccharide (can’t be hydrolysed to give a simpler sugar) sugar molecule with the chemical formula of C5H10O5 that helps form the phosphate backbone of DNA molecules.

29
Q

What is a phosphate group?

A

A phosphate group is what we call a phosphate molecule after it’s been attached to a molecule containing carbon.
A phosphate molecule is a chemical compound made up of one phosphorus (P) and four oxygen atoms (O).

30
Q

What is a nitrogenous base?

A

A nitrogenous base is an organic molecule that contains the element nitrogen and acts as a base in chemical reactions.

31
Q

What is another name for a nitrogenous base?

A

A nucleobase.

32
Q

List the nitrogenous bases in DNA.

A
  • Adenine
  • Thymine (replaced by Uracil in RNA)
  • Guanine
  • Cytosine.
33
Q

What is adenine?

A

Adenine is a purine nucleobase that pairs with thymine in double stranded DNA.

34
Q

What is thymine?

A

Thymine is a pyrimidine nucleobase that pairs with adenine in double stranded DNA.

35
Q

What is cytosine?

A

Cytosine is a pyrimidine nucleobase that pairs with guanine in double stranded DNA.

36
Q

What is guanine?

A

Guanine is a purine nucleobase that pairs with cytosine in double stranded DNA.

37
Q

What is a purine?

A

A purine is a crystalline base with the chemical formula C5H4N4 that is a parent compound of the uric-acid group and have two-carbon nitrogen ring bases.
The purine molecules in DNA are adenine and guanine.

38
Q

What is a pyrimidine?

A

A pyrimidine is a simple aromatic compound with the formula C4H4N2 and one-carbon nitrogen ring base.
The pyrimidines found in DNA are cytosine and thymine.

39
Q

What are hydrogen bonds?

A

Hydrogen bonds are electrostatic forces of attraction between a hydrogen atom in one polar molecule and a smaller electronegative atom in usually another molecule in a polar substance.

40
Q

Define the term “gene”.

A

A gene is a short segment on DNA with a specific sequence of nitrogenous bases that codes for a particular protein. A gene is the basic physical and functional unit of heredity.

41
Q

Define the term “genome”.

A

A genome is the complete set of genes in an organism.

42
Q

What is DNA replication?

A

DNA replication is the duplication of the DNA molecule to form two identical copies (replicas) and takes place during the interphase stage of the cell cycle.

43
Q

What is protein synthesis?

A

Protein synthesis is a multi-step process in which cells take the coded message of DNA and convert it into a usable protein molecule.

New Keycard:
It occurs in two stages: transcription and translation. Transcription is the transfer of genetic instructions in DNA to mRNA in the nucleus. It includes three steps: initiation, elongation, and termination.

44
Q

What are amino acids?

A

Amino acids are organic compounds that combine to form proteins.

45
Q

What is “coding DNA”?

A

Coding DNA is a sequence of DNA that encodes for protein. It is also known as an Exon.

46
Q

What is “non-coding DNA”?

A

Non-coding DNA is a type of DNA that contains sequences that act as regulatory elements but does not contain the code for synthesising proteins.

47
Q

What is gene expression?

A

Gene expression is the process by which the instructions in DNA are converted into a functional product, such as a protein.
It acts as both an on/off switch to control when proteins are made and also a volume control that increases or decreases the amount of proteins made.

48
Q

Define the term “mutation” in relation to DNA.

A

A mutation is a permanent alteration/change in a DNA sequence.
Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.

49
Q

What is a ‘complementary strand” of DNA?

A

A complementary strand of DNA is a strand that forms from free nucleotides that join to their complementary bases on a template strand of DNA.

50
Q

Define the term “interphase” in the context of cell division.

A

Interphase is a phase in which a cell grows and DNA replication occurs in preparation for the actual division of a mother cell during mitosis.

50
Q

Define the term “DNA template”.

A

DNA templates are two strands of DNA that come from an original chromosome that are prepared to have free nucleotides attach to them in complementary pairs to form two identical strands of DNA.

51
Q

Define the term “enzymes”.

A

Enzymes are proteins that catalyse the reaction of weak hydrogen bonds breaking during DNA replication. E.g. DNA Polymerase.

52
Q

Define the term “free nucleotides”.

A

Free nucleotides are sugar molecules, phosphate groups, and nitrogen base complexes that are unattached to a DNA or RNA strand and are available for base pairing in the nucleoplasm.

53
Q

Define the term “daughter cell” in relation to mitotic cell division.

A

A daughter cell refers to one of two cells that are formed when a cell undergoes cell division by mitosis and is genetically identical to the parent cellDaughter cells are genetically identical to the parent cell because they contain the same number and type of chromosomes.

54
Q

Define the term “mother cell” in relation to mitotic cell division.

A

The mother cell refers to one cell that divides to produce two new cells that are genetically identical to itself and each other (in the case of mitosis).

55
Q

Define the term “biological inheritance”.

A

Biological inheritance is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, and the offspring cells or organisms acquire the genetic information of their parents.

56
Q

Define the term “DNA profile”.

A

DNA profiling is a forensic technique used to identify individuals based on differences, or variations, in their DNA sequence.

57
Q

Define the term “DNA sample”.

A

A DNA sample is a smaller quantity of DNA that can be collected to compare DNA patterns in DNA profiling.

58
Q

Define the term “DNA extraction”.

A

DNA extraction is a routine procedure used to isolate and remove DNA from the nucleus of cells.

59
Q

What does the term “identical twins” mean?

A

Identical twins (aka monozygotic twins) are a pair of twins formed from the separation of the same fertilized embryo to form two genetically identical zygotes.

60
Q

Define the term “forensic evidence”.

A

Forensic evidence is DNA evidence from biological specimens (e.g. skin, blood, saliva, semen or hair) that can be collected at a crime scene and used in a court of law.

61
Q

Define the term “paternity”.

A

Paternity describes the role/relationship a man has of being a father to his biological child(ren).

62
Q

What does the term “endangered species” mean?

A

Endangered species are species of animals or plants that are at serious risk of extinction.

63
Q

Define the term “poaching”.

A

Poaching is when a living organism is illegally hunted, caught, or removed from land without the land owner’s permission or in disregard for the laws surrounding the organism’s official protection.

64
Q

Define the term “DNA barcode”.

A

A DNA barcode is a ‘barcode’ pattern that every individual has, using non-coding DNA where the pattern of the bars coincides with the sequence of base pairs inherited from their parents.

65
Q

Define the term “genetic disease”.

A

A genetic disease is an inherited medical condition caused by a DNA abnormality such a mutation or change of an individual’s DNA sequence.