DNA structure Flashcards

1
Q

DNA and RNA similarities

A

both types of nucleic acid
both found in all living cells
both needed to build proteins - essential for proper functioning of cells.
both important information carrying molecules (although they have different functions.)

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2
Q

DNA function

A

store genetic information
contains the instructions for the growth and development of all organisms

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3
Q

RNA function

A

To transfer genetic code found in DNA out of the nucleus and carry it to the ribosomes in the cytoplasm.

Ribosomes are where proteins are produced - they read the RNA to make polypeptides (proteins) in a process called translation.

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4
Q

what are the monomers of DNA and RNA called

A

nucleotides

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5
Q

what is a nucleotide made of?

A

A pentose sugar
A nitrogen-containing organic base
A phosphate group

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6
Q

DNA nucleotides components

A

A deoxyribose sugar with hydrogen at the 2’ position
A phosphate group
One nitrogenous base

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7
Q

RNA components

A

A ribose sugar with a hydroxyl group at the 2’ position
A phosphate group

One nitrogenous base but thymine is replaced with uracil.

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8
Q

RNA and DNA differences

A

Pentose sugar (ribose and deoxyribose)
Bases (T for U)
Number of strands (double and single)

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9
Q

How do nucleotides join?

A

condensation reaction

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10
Q

what is the chain of alternating phosphate groups and pentose sugars called?

A

Sugar-phospate backbone.

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11
Q

Draw a DNA nucleotide

A

pentose sugar, labled as follows:
Oxygen at northen peak
1’ should be on right corner
The numbers should increase clockwise
attached to 1’ should be a nitrogenous base
a hydrogen should drop from 2’
phosphate group should comef rom 4’ and make a 5’ CH2 group.

Phosphate group is circle
nitrogenous base is rectangle
Pentose sugar is pentagon.

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12
Q

how do bases bond?

A

hydrogen bonds between complimentry base pairs.
complimentry base pairing.

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13
Q

how many hydrogen bonds between the bases?

A

T=A - 2
C≡G - 3

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14
Q

what is the double helix

A

the three dimentional shape that DNA molecules form.

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15
Q

Draw a RNA nucleotide

A

pentose sugar, labled as follows:
Oxygen at northen peak
1’ should be on right corner
The numbers should increase clockwise
attached to 1’ should be a nitrogenous base
a hydroxyl group should drop from 2’
phosphate group should comef rom 4’ and make a 5’ CH2 group.

Phosphate group is circle
nitrogenous base is rectangle
Pentose sugar is pentagon.

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16
Q

What are ribosomes made of? how does it help with making protiens.

A

RNA and protiens
(ribosomal RNA) - able to catalyse the formation of peptide bonds between amino acids.

17
Q

what are 80S and 70S ribosomes made up of?

A

80S - 60S and 40S
70S - 50S and 30S

18
Q

where are 70S ribosomes found?

A

Prokaryotic cells + mitocondria + chloroplasts.

19
Q

what happens in the larger subunit of ribosomes?

A

translation

20
Q

what happens in translation?

A

the rRNA hold tRNA in place
rRNA catalyses the condensation reactions between amino acids.

21
Q

mRNA role in translation

A

sits between the two ribosome subunits and the ribosome moves along it as it translates it into a polypeptide.

22
Q

ribosome membrane?

A

NO

23
Q

Give me a rundown on why scientists didn’t believe in the model of DNA, remember to name the 3 people.

A

Doubted it could carry genetic code
too simple
only simple repeating nucleotides
20 different amino acids
4 different nucleotides
watson and crick confirmed double helix structure of DNA using Rosalind Franklin’s x-ray data.