DNA,RNA, Protein Synthesis Flashcards

1
Q

What does DNA stand for?

A

Deoxyribonucleic Acid

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2
Q

What are the building blocks (monomers) of DNA?

A

Nucleotide

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3
Q

What are the 3 parts of a nucleotide?

A

Phosphate group, 5 carbon sugar, nitrogenous base

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4
Q

What are the 4 nitrogen bases present in DNA?

A

Adenine, Thymine, Guanine, Cytosine

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5
Q

What are Purines? How many rings do they have?

A

Adenine/Guanine, 2

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6
Q

What are pyrimidines? How many rings do they have?

A

Thymine/Cytosine, 1

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7
Q

The double helix structure of DNA was discovered by 4 scientists - what are their names and what was the year?

A

James Watson(1953), Francis Crick(1953), Rosalind Franklin(1952), Maurice Wilkins(1951)

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8
Q

What did Erwin Chargaff discover?

A

ratios of (A) to (T) and (G) to (C) are equal

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9
Q

What is the “backbone” of DNA made up of?

A

Deoxyribose and phosphate groups

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10
Q

What holds the DNA molecule together?

A

Hydrogen bonds

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11
Q

The nitrogen bases are always connected to the (sugar or phosphate)?

A

Sugar

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12
Q

Name the complementary strands of a DNA molecule.

A

Adenine (A) is always paired with Thymine (T), and Cytosine (C) is always paired with Guanine (G)

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13
Q

What enzyme “unzips” the 2 strands of DNA in DNA replication?

A

DNA Helicase

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14
Q

What does DNA polymerase do?

A

“Zips up 2 strands of DNA, one preexisting strand and a new strand”

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15
Q

If one strand of DNA if ATT CCG, what is the other complementary strand of DNA?

A

TAA GGC

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16
Q

What are the 3 types of RNA? What does each type do?

A

Messenger:Carries genetic info of DNA from nucleus to cytoplasm
Transfer:Carries amino acids to ribosome
Ribosomal:Metabolic molecule aids in protein synthesis

17
Q

What are 4 differences between RNA and DNA?

A

DNA is double-stranded/ RNA is usually single-stranded
DNA is deoxyribose/RNA contains ribose
DNA uses the bases A,T,C,G/RNA uses A,C,G and Uracil

18
Q

What is transcription? Where does it occur in the cell (nucleus or cytoplasm)?

A

RNA molecules produced by copying part of the nucleotide sequence of DNA into complementary sequence in RNA/ Nucleus

19
Q

Briefly describe the steps of transcription.

A

Enzyme called RNA polymerase binds to promoter site
Seperation of complementary DNA strands
RNA polymerase uses one strand of DNA as template, nucleotides assembled into a strand of RNA
RNA polymerase reaches termination site, new RNA released
RNA moves from nucleus to cytoplasm

20
Q

What enzyme is responsible for transcription?

A

RNA Polymerase

21
Q

How does mRNA move from the nucleus to the cytoplasm of a cell?

A

Read by ribosome to make a protein in cytoplasm, Protein synthesis transports, moves, protects, supports, communicates, regulates

22
Q

If an RNA molecule contains the sequence AAC GCU, what is the sequence of the DNA molecules from which it was made?

23
Q

A series of 3 mRNA nitrogen bases that contains the information needed to make proteins are called what?

24
Q

What is the universal start codon and what amino acid does it code for?

A

AUG Methionine

25
What are the 3 stop codons?
UAA, UAG, UGA
26
What is translation? Where does it occur in the cell (nucleus or cytoplasm)?
Sequence of nitrogenous bases in new RNA strand translated into amino acids/ cytoplasm
27
Find the mRNA strand, tRNA anticodon and amino acid sequence for the following DNS strand: TAC CCT CAT ACT
AUG GGA GUA UGA UAC CCU CAU ACU Iso Pro His Thre
28
What does the word “mutation” mean?
A change in the structure of the genes or chromosomes of an organism
29
Mutations that produce changes in a single gene are called ____
Gene Mutation
30
Mutations that produce changes in whole chromosomes are known as _____
Chromosomal Mutation
31
In what way(s), if any, do most mutations change organisms?
changing its physical characteristics
32
What are the 3 examples of gene (point) mutations?
Substitution, Insertion, Deletion
33
Insertions and deletions usually result in frameshift mutations. What does this mean?
The Frame or the way you read the RNA strand shifts left or right
34
What are the 4 examples of chromosomal mutations? Explain each.
deletion, duplication, inversion, and translocation