DNA,RNA, Protein Synthesis Flashcards
What does DNA stand for?
Deoxyribonucleic Acid
What are the building blocks (monomers) of DNA?
Nucleotide
What are the 3 parts of a nucleotide?
Phosphate group, 5 carbon sugar, nitrogenous base
What are the 4 nitrogen bases present in DNA?
Adenine, Thymine, Guanine, Cytosine
What are Purines? How many rings do they have?
Adenine/Guanine, 2
What are pyrimidines? How many rings do they have?
Thymine/Cytosine, 1
The double helix structure of DNA was discovered by 4 scientists - what are their names and what was the year?
James Watson(1953), Francis Crick(1953), Rosalind Franklin(1952), Maurice Wilkins(1951)
What did Erwin Chargaff discover?
ratios of (A) to (T) and (G) to (C) are equal
What is the “backbone” of DNA made up of?
Deoxyribose and phosphate groups
What holds the DNA molecule together?
Hydrogen bonds
The nitrogen bases are always connected to the (sugar or phosphate)?
Sugar
Name the complementary strands of a DNA molecule.
Adenine (A) is always paired with Thymine (T), and Cytosine (C) is always paired with Guanine (G)
What enzyme “unzips” the 2 strands of DNA in DNA replication?
DNA Helicase
What does DNA polymerase do?
“Zips up 2 strands of DNA, one preexisting strand and a new strand”
If one strand of DNA if ATT CCG, what is the other complementary strand of DNA?
TAA GGC
What are the 3 types of RNA? What does each type do?
Messenger:Carries genetic info of DNA from nucleus to cytoplasm
Transfer:Carries amino acids to ribosome
Ribosomal:Metabolic molecule aids in protein synthesis
What are 4 differences between RNA and DNA?
DNA is double-stranded/ RNA is usually single-stranded
DNA is deoxyribose/RNA contains ribose
DNA uses the bases A,T,C,G/RNA uses A,C,G and Uracil
What is transcription? Where does it occur in the cell (nucleus or cytoplasm)?
RNA molecules produced by copying part of the nucleotide sequence of DNA into complementary sequence in RNA/ Nucleus
Briefly describe the steps of transcription.
Enzyme called RNA polymerase binds to promoter site
Seperation of complementary DNA strands
RNA polymerase uses one strand of DNA as template, nucleotides assembled into a strand of RNA
RNA polymerase reaches termination site, new RNA released
RNA moves from nucleus to cytoplasm
What enzyme is responsible for transcription?
RNA Polymerase
How does mRNA move from the nucleus to the cytoplasm of a cell?
Read by ribosome to make a protein in cytoplasm, Protein synthesis transports, moves, protects, supports, communicates, regulates
If an RNA molecule contains the sequence AAC GCU, what is the sequence of the DNA molecules from which it was made?
TTG CGA
A series of 3 mRNA nitrogen bases that contains the information needed to make proteins are called what?
Codon
What is the universal start codon and what amino acid does it code for?
AUG Methionine