DNA Repair And Cell Cycle

Question 1

Describe the general outline of the different phase of the eukaryotic cell, including G0

Answer 1

Y

Question 2

Appreciate the complexity of cell cycle control and the consequence of loss of control

Answer 2

I

Question 3

Describe the variety of exogenous and endogenous factors that can cause DNA damage

Answer 3

K

Question 4

Give examples of types of DNA damage

Answer 4

M

Question 5

Describe in general terms what is meant by replication stress

Answer 5

I

Question 6

Outline and explain how fork slippage cause mutations

Answer 6

Y

Question 7

Explain and describe the DNA damage response

Answer 7

I

Question 8

Compare and describe in general terms of number of single strand breaks repair mechanism and double strand repair mecahnisms

Answer 8

C

Question 9

Appreciate the potental consequences of error-prone double strand repair

Answer 9

B

Question 10

Describe in general terms what is meant by tumour heterogeneity and cancer evolution

Answer 10

P

Question 11

Describe the complex relationship between mutations, DNA repair and cancer

Answer 11

Z