DNA Repair

Question 0

Common theme in DNA repair.?

Answer 0

• recognition of issue
• fix the issue
• repairs depend on the type of damage.All repairs are not the same.

Question 1

DNA must me repair before ___________?

Answer 1

DNA must be fixed before replication .( except for retroviruses & transposons b/c they can’t be removed )

Question 2

Types of DNA repair .

Answer 2

Direct DNA repair

• -direct repair of thymine dimers
• -direct repair of alkylated bases

Indirect repair

• -excision repair
• -base excision repair
• -NER nucleotide excision repair
• • mismatch repair

Fixing double stranded damage

• -homologous recombination repair
• -non-homologous recombination repair