DNA, Genes And Chromosomes Flashcards

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1
Q

Nuclear eukaryotic DNA is ____________

A

Linear

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2
Q

Describe the structure of DNA

A
  • long, can be wound up by just ones
  • double helix
  • linear
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3
Q

How and why does prokaryotic DNA condense?

A

It supercoils could to fit within the cell

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4
Q

What does DNA contain?

A

Genes

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5
Q

What is a gene?

A

A sequence of DNA bases that code for polypeptide or functional RNA

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6
Q

What determines the order of amino acid within a polypeptide?

A

The order of bases

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7
Q

What sections make up DNA?

A
  • exons and introns
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8
Q

What are exons?

A

Genes that do code for polypeptides

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9
Q

What are introns?

A

Non-coding genes within a sequence

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10
Q

What are alleles?

A

Genes that exist in more than one form

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11
Q

What are the two types of RNA?

A

mRNA- carries genetic code from DNA to Ribosomes
tRNA- used in translation, carries specific amino acids to ribosomes, it has a clover shape

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12
Q

What is the first stage of Protein Synthesis?

A

Transcription

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13
Q

Describe the process of protein synthesis

A
  1. RNA helicase attached to DNA helix at the beginning of a gene
  2. Hydrogen bonds between the two strands are hydrolysed separating the strand and uncoiling it
  3. One of the strands it’s then used as a template to make an mRNA copy
  4. RNA polymerase joins together free nucleotides to the base via complimentary base pairing, AU, CG
  5. RNA polymerase moves along the DNA separating the strands and assembling the pre-mRNA strand
  6. Hydrogen bonds between the uncoiled DNA reform and coil the DNA strands back into a double helix
  7. When RNA polymerase reaches a stop signal it detached from the DNA
  8. pre-mRNA is spliced and then moves out of the nucleus through the pore
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14
Q

What’s the second stage of Protein Synthesis?

A

Translation

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15
Q

Describe the process of Translation

A
  1. mRNA attaches to a ribosome and tRNA then carry the specific amino acids to it, ATP providing the energy needed
  2. A tRNA molecule with an anticodon that’s that’s complimentary to the first codon on the mRNA attaches to the mRNA via specific base pairing
  3. A second tRNA molecule attaches to the next codon on the mRNA the same way
  4. The two amino acids attached to the tRNA molecules are joined via a peptide bond
  5. A third tRNA molecule binds to the next codon on mRNA
  6. This process continues, forming a polypeptide chain
  7. The polypeptide chain moves away from the ribosome and translation is complete
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