DNA Damage, Repair, and Mutation

Question 1

What is a mutation?

Answer 1

A mutation is a change in DNA sequences that can be passed from one cell to its daughter cells.

Question 2

What is a gene mutation?

Answer 2

A gene mutation is a mutation that is due to a change in the DNA sequences of a small segment of DNA that affects the DNA sequences of (at most) one gene

Question 3

What is a forward mutation?

Answer 3

A forward mutation is a mutation that goes from WT version to not WT gene

Question 4

What is a reverse mutation?

Answer 4

A mutation of non WT back to WT

Question 5

True or False: Mutations can occur in any cell of the body.

Answer 5

True - Mutations can occur in any cell of the body.

Question 6

What is a germline mutation?

Answer 6

If the mutation occurs in the reproductive cells, it can be passed from one generation to the next by sexual reproduction.

Question 7

What are somatic/vegetative mutations?

Answer 7

Mutations in the non-reproductive cells of the body but they would NOT be passed to the next generation.

Question 8

If a person inherits a germline mutation from their parents, then they have the mutation in their entire body.

Answer 8

Offspring would have BOTH a germline and somatic mutation.