DNA and RNA Flashcards

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1
Q

What does DNA do?

A

Deoxyribose nucleic acid (DNA) codes for the sequence of amino acids in the primary structure of a protein, which in turn determine the final structure and function of a protein.

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2
Q

What monomer makes up DNA?

A

A nucleotide

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3
Q

What is a DNA molecule made up of?

A
  • Deoxyribose (pentose sugar)
  • A nitrogenous base
  • Phosphate group
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4
Q

What is the polymer of a nucleotide called?

A

Polynucleotide

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5
Q

How is a polynucleotide made?

A

It is created via a condensation reaction between the deoxyribose sugar and the phosphate group, creating a phosphodiester bond

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6
Q

How is the double helix held together?

A

Hydrogen bonds between the base pairs

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7
Q

What is RNA?

A

It is a polymer of a nucleotide formed of ribose, a nitrogenous base and a phosphate group

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8
Q

Features of DNA?

A
  • In the nucleus
  • Large
  • Deoxyribose
  • C,G,A,T
  • Double helix
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9
Q

Features of RNA?

A
  • Small
  • Ribose
  • Nucleus, cytoplasm, ribosome
  • C,G,A,U
  • Single stranded
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10
Q

What is the function of RNA?

A

The function of RNA is to transfer the genetic code from DNA in the nucleus to the ribosomes. Some RNA is also combined with proteins to create ribosomes

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11
Q

What is DNA replication?

A

Before cells divide all the DNA must replicate to provide a copy for the new cell
The process of DNA replication is semi- conservative replication (in the parental DNA and one strand is newly synthesised)

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12
Q

What is semi- conservative replication?

A
  • DNA helicase breaks the hydrogen bonds between the complementary base pairs between the 2 strands within a double helix, this causes the double helix to unwind.
  • Each of the separated strands of DNA act as a template. Free floating DNA nucleotides within the nucleus are attracted to their complementary base pairs on the template strands of the parental DNA.
  • The adjacent nucleotides are joined together (to form a phosphodiester bond) by a condensation reaction. DNA polymerase catalyses the joining together of adjacent nucleotides.
  • The 2 sets of daughter DNA contains one strand of the parental DNA and one newly synthesised strand.
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13
Q

Who discovered the structure of DNA?

A

Watson and Crick in 1953 with the help of Rosalind Franklin

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14
Q

Who conducted the experiment which proved DNA replication must be semi- conservative?

A

Meselson and Stahl

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15
Q

What is ATP?

A

It is an immediate source of energy for biological processes.

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16
Q

How is ATP made?

A

ATP is made during respiration from ADP + Pi using enzyme ATP hydrolase. This releases a small amount of energy.

17
Q

What is released during the hydrolysis of ATP?

A

An inorganic ion

18
Q

What bond forms between water molecules?

A

Hydrogen bonds

19
Q

The 5 key properties of water

A
  • It is a metabolite (in condensation and hydrolysis reactions)
  • An important solvent in reactions
  • Has a high heat capacity, it buffers temperatures
  • Has a large latent heat capacity of vaporisation, providing a cooling effect with loss of water through evaporation
  • Has strong cohesion between water molecules, this supports water columns and provides surface tension
20
Q

What does solvent mean?

A

It means to dissolve

21
Q

What is latent heat?

A

How much heat to change a liquid to a gas. It cools the body down (sweating)

22
Q

What is high specific heat?

A

Energy required to raise temperature by 1 degree C

23
Q

What does cohesion mean?

A

Molecules stick together

24
Q

What are inorganic ions?

A

Inorganic ions occur in solution in the cytoplasm and body fluids of organisms

25
Q

Different types of inorganic ions

A

Hydrogen bonds- lower the pH of solutions and impact enzyme function and haemoglobin function
Iron ions- A component of haemoglobin in the transport of oxygen
Sodium ions- Involved in the co- transport of glucose and amino acids in absorption
Phosphate ion- A component of DNA (forms phosphodiester bonds with deoxyribose) and ATP (makes it more reactive)