DNA and RNA Flashcards
What does DNA do?
Deoxyribose nucleic acid (DNA) codes for the sequence of amino acids in the primary structure of a protein, which in turn determine the final structure and function of a protein.
What monomer makes up DNA?
A nucleotide
What is a DNA molecule made up of?
- Deoxyribose (pentose sugar)
- A nitrogenous base
- Phosphate group
What is the polymer of a nucleotide called?
Polynucleotide
How is a polynucleotide made?
It is created via a condensation reaction between the deoxyribose sugar and the phosphate group, creating a phosphodiester bond
How is the double helix held together?
Hydrogen bonds between the base pairs
What is RNA?
It is a polymer of a nucleotide formed of ribose, a nitrogenous base and a phosphate group
Features of DNA?
- In the nucleus
- Large
- Deoxyribose
- C,G,A,T
- Double helix
Features of RNA?
- Small
- Ribose
- Nucleus, cytoplasm, ribosome
- C,G,A,U
- Single stranded
What is the function of RNA?
The function of RNA is to transfer the genetic code from DNA in the nucleus to the ribosomes. Some RNA is also combined with proteins to create ribosomes
What is DNA replication?
Before cells divide all the DNA must replicate to provide a copy for the new cell
The process of DNA replication is semi- conservative replication (in the parental DNA and one strand is newly synthesised)
What is semi- conservative replication?
- DNA helicase breaks the hydrogen bonds between the complementary base pairs between the 2 strands within a double helix, this causes the double helix to unwind.
- Each of the separated strands of DNA act as a template. Free floating DNA nucleotides within the nucleus are attracted to their complementary base pairs on the template strands of the parental DNA.
- The adjacent nucleotides are joined together (to form a phosphodiester bond) by a condensation reaction. DNA polymerase catalyses the joining together of adjacent nucleotides.
- The 2 sets of daughter DNA contains one strand of the parental DNA and one newly synthesised strand.
Who discovered the structure of DNA?
Watson and Crick in 1953 with the help of Rosalind Franklin
Who conducted the experiment which proved DNA replication must be semi- conservative?
Meselson and Stahl
What is ATP?
It is an immediate source of energy for biological processes.