DNA and Protein Synthesis Vocab pt.2 Flashcards
Central Dogma
DNA (transcription) –> RNA (translation) –> protein
mRNA (messenger)
copies instructions in DNA and carries there to the ribosomes in the cytoplasm
rRNA (ribosomal)
- makes up ribosomes (along with proteins)
- helps catalyze formation of peptide bonds
tRNA (transfer)
binds and carries certain amino acids to the ribosome
Transcription
- takes place in the nucleus
- when DNA is copied into a complementary strand of mRNA
Translation
- takes place in ribosomes
- instructions carried on mRNA is read to make a polypeptide
Polypeptide
- chain of amino acids
- bind to others + fold into protein
Start Codon
- AUG (Met)
- first codon in transcribed mRNA that goes through translation
Stop codon
- UAG, UAA, UGA
- signals end of making of polypeptide during translation
Introns
non-coding regions
Exons
coding regions
Transcription Factors
regulatory proteins which control the activity of the gene
Mutation
a change in the DNA sequence
Frameshift mutation
- type of mutation involving insertion/deletion of nucleotide
- number of deleted base pairs is not divisible by 3
Insertion (mutation)
type of mutation which additionally involves genetic material