DNA and Protein Synthesis Flashcards
What are the 4 complementary bases?
Guanine - Cytosine
Thymine - Adenine
What holds complementary base pairs together?
Weak hydrogen bonds
How many hydrogen bonds hold Guanine and Cytosine together?
3
How many hydrogen bonds hold Thymine and Adenine together?
2
What holds nucleotides together?
Strong chemical bonds
Describe the structure of DNA
DNA is a double stranded helix with a sugar-phosphate backbone. The strands run anti-parallel to each other and is arranged so that it tightly coils into a chromosome
Explain stage 1 of DNA replication
Double helix unwinds using the enzyme helicase
Explain stage 2 of DNA replication
Weak hydrogen bonds between complementary base pairs break and cause the two DNA strands to unzip
Explain stage 3 of DNA replication
Free DNA nucleotides from the nucleoplasm enter join their complimentary base pair on the open strand using DNA polymerase
Explain stage 4 of DNA replication
Weak hydrogen bonds begin to reform between base pairs
Explain stage 5 of DNA replication
Strong chemical bonds form between nucleotides controlled by the enzyme polymerase
Explain stage 6 of DNA replication
The 2 strands begin to form back into a double helix. 2 newly formed daughter strands are created that are identical to the parent/original strand.
What is DNA Polymerase?
DNA Polymerase controls the sugar-phosphate bonding between nucleotides on the new DNA strand.
What type of replication is DNA replication known as?
Semi-conservative replication as one strand from the original DNA molecule is used in the twodaughter molecules
What is a DNA primer?
A DNA primer initiates DNA replication and is always on the third carbon of the original strand