DNA Flashcards

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1
Q

What is the structure of DNA?

A

double helix = 2 polynucleotide strands wound round eachother joined by hydrogen bonds between the bases

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2
Q

How many hydrogen bonds between A and T ?

A

two

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3
Q

How many hydrogen bonds between G and C ?

A

three

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4
Q

Who discovered the structure of DNA?

A

James and Watson and Francis Crick in 1953

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5
Q

What is the structure of a DNA nucleotide?

A

pentose sugar = called deoxyribose which has 5 carbon atoms
phosphate group = negatively charged
organic nitrogen base - have two groups
1.) single ring bases - cystosine (C) and thymine (T) - pyrimidines
2.) double ring bases - adenine (A) and guanine (G) - purines

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6
Q

What is the structure of a DNA polynucleotide?

A
  • many nucleotides joined together via a condensation reaction between the phosphate group of one nucleotide and the sugar of another creating a phosphodiester bong - stronger than covalent to ensure that the genetic code is not broken
  • has a sugar phosphate backbone - the strong covalent bonds between the sugar and phosphate groups that hold the polymer together
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7
Q

What is the function of DNA?

A
  • stores your genetic info (instructions needed to grow + develop)
  • passes on genetic info from cell to cell
  • codes for the sequence of amino acids int he primary structure of a protein which in turn determines the final 3D structure and function of a protein
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8
Q

How does the structure of DNA relate to its function?

A
  • very stable due to sugar phosphate backbone (covalent bonds) + double helix
  • weak hydrogen bonds –> strands can separate during DNA replication and protein synthesis
  • double stranded so replication can occur using one strand as a template (semi-conservative replication)
  • phosphodiester backbone protects more chemically reactive bases inside helix
  • large molecule so it can carry lots of genetic info
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