DNA Flashcards
What is the structure of DNA?
double helix = 2 polynucleotide strands wound round eachother joined by hydrogen bonds between the bases
How many hydrogen bonds between A and T ?
two
How many hydrogen bonds between G and C ?
three
Who discovered the structure of DNA?
James and Watson and Francis Crick in 1953
What is the structure of a DNA nucleotide?
pentose sugar = called deoxyribose which has 5 carbon atoms
phosphate group = negatively charged
organic nitrogen base - have two groups
1.) single ring bases - cystosine (C) and thymine (T) - pyrimidines
2.) double ring bases - adenine (A) and guanine (G) - purines
What is the structure of a DNA polynucleotide?
- many nucleotides joined together via a condensation reaction between the phosphate group of one nucleotide and the sugar of another creating a phosphodiester bong - stronger than covalent to ensure that the genetic code is not broken
- has a sugar phosphate backbone - the strong covalent bonds between the sugar and phosphate groups that hold the polymer together
What is the function of DNA?
- stores your genetic info (instructions needed to grow + develop)
- passes on genetic info from cell to cell
- codes for the sequence of amino acids int he primary structure of a protein which in turn determines the final 3D structure and function of a protein
How does the structure of DNA relate to its function?
- very stable due to sugar phosphate backbone (covalent bonds) + double helix
- weak hydrogen bonds –> strands can separate during DNA replication and protein synthesis
- double stranded so replication can occur using one strand as a template (semi-conservative replication)
- phosphodiester backbone protects more chemically reactive bases inside helix
- large molecule so it can carry lots of genetic info