Dna Flashcards
What is DNA and RNA
Both essential for the function of living organisms. Both types of nucleic acid. Found in all living cells and carry information
DNA ( Deoxyribonucleic acid)
Used to store genetic information (instructions needed to grow and develop from a fertilised egg to a fully grown adult)
RNA ( Ribonucleic acid)
Similar structure to DNA
Main function is to transfer genetic information from the DNA to the ribosomes . Ribosomes themselves are made of RNA and proteins
Nucleotide structure
DNA AND RNA are polymers of nucleotides. A Nucleotide is a biological molecule made from three different components. A pentose sugar ( sugar with 5 carbon ) nitrogen containing organic base and a Phosphate group
Polynucleotide structure
Many nucleotides join to form polynucleotide strands ( or chains) join via condensation reaction between the phosphate group of one nucleotide and the sugar of another.
Forms a phosphodiester bond (phosphate group and two ester bonds).
Sugar phosphate backbone
Chain of phoshates and sugar
DNA structure
Double helix structure.
Formed by two separate strands that wind round each other to form a spiral. ( strands called polynucleotides)
DNA molecules are very long and coiled very tightly so genetic info can fit into a small space in the cell nucleus
DNA nucleotide structure
Made from a phosphate group, the pentose sugar, deoxyribose and a nitrogen containing organic base
Has same sugar and phosphate, base on each nucleotide can vary though.
Four bases adenine, thymine, cytosine, guanine
Complementary base pairing
Two DNA polynucleotide strands join together by hydrogen bonds between the bases. Each base can join with one specific partner called complementary base pairing. Adenine with thymine ( A - T) and guanine always pairs with cytosine ( G - C)
Number of hydrogen bonds between each base?
Two hydrogen bonds between A (adenine) and T (thymine)
Three hydrogen bonds between C (cytosine) and G (guanine)
Two polynucleotide strands are antiparallel. Two of these strands twist to form a DNA double helix
RNA Structure
Differs to DNA:
Sugar in RNA nucleotides is a ribose sugar (not deoxyribose)
Uracil (u) replaces thymine as a base and pairs with adenine
Nucleotide form a single polynucleotide strand (not double)
Strands much shorter than most DNA