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Pharm Exam 3 > DMARDs BRMs > Flashcards

DMARDs BRMs Flashcards

1
Q

Medications that therapeutically alter a patient’s immune response to malignant tumor cells

A

Immunomodulating

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2
Q

promote the synthesis of various types of major blood

A

Hematopoietic

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3
Q

increases WBC levels: wait 24 hrs

A

Filgrastim

CSFs

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4
Q

Platelet-promoting drugs; stimulates bone marrow

A

Oprelvekin

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5
Q

When severely anemic give:

A

Epoetin alfa

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6
Q

Longer acting form of filgrastim

A

pegfilgrastim

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7
Q

Indicated for the prevention of chemotherapy-induced severe thrombocytopenia and avoidance of the need for platelet transfusions

A

oprelvekin

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8
Q

advantage of hematopoietic drugs

A

to manage anemia; neutropenia; thrombocytopenia

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9
Q

Hematopoietic Drugs:Adverse Effects

A

Fever
Muscle aches
Bone p!
Flushing

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10
Q

Interferons indications

A

Viral infections: warts hepatitis

Autoimmune: MS; RA

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11
Q

Monoclonal Antibodies treat

A

RA, MS

“mumab”

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12
Q

Interferons adverse effects

A

Dose-limiting adverse effects is fatigue

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13
Q

Monoclonal Antibodies targets

A

cancer cells instead minimal effects on healthy cells

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14
Q

Antirehumatic drug:

A

methotrexate

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15
Q

Used to treat RA

A

Abatacept (Orencia)

Hydroxychloroquine

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16
Q

Abatacept: must be

A

up to date on immunizations-do not give live vaccines

17
Q

Etanercept (Enbrel) &

A

latex allergy

contraindicated for hepatitis & tTB

18
Q

Takes 3 to 6 weeks for onset of antirheumatic action

A

methotrexate

19
Q

condition that results from inappropriate uric acid metabolism

A

Gout

20
Q

Gout drugs

A

allopurinol (control uric acid in blood; prevention)

Colchicine (acute treatment; short term management)

21
Q

Allopurinol watch out for

A

tumor lysis syndrom
SJ syndrome
toxic epidermal necrolysis

22
Q

Allopurinol watch for also:

A

renal stones; monitor uric acid levels

23
Q

Treatment of cancer, rheumatoid arthritis (RA), MS, and organ transplantation
Specifically target cancer cells and have minimal effect on healthy cells

A

monoclonal antibodies

24
Q

Etanercept (Enbrel) &

A

Contraindicated in presence of active infections

Reactivation of hepatitis and tuberculosis has been reported.

Pharm Exam 3 (7 decks)

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