DMARDs Flashcards
1
Q
RA cause
A
cytokine induction of destructive enzymes including:
MMPs = matrix metalloproteases
IL- 1
TNF alpha
2
Q
NSAIDs/corticosteroids in RA
A
they reduce symptoms but do not retard progression of disease
3
Q
DMARDs
A
should stop progression of disease
4
Q
biologics
A
newer drugs and used when DMARD hasnt stopped progression of the disease or patient cannot tolerate the side effect profile
5
Q
DMARDs cocktail
A
cocktail of drugs initially as DMARDs taken 4 - 6 months to kick in
NSAID + corticosteroids + DMARDs
