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Biologicos > DMARDs > Flashcards

DMARDs Flashcards

1
Q

Enzima metaboliza Azatioprina

A

Metilttansferase
- Metabolizador lento aumenta toxicidade

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2
Q

UPA, Tofa e Bari quais JAKs?

A

Tofa 1 e 3
UPA 1
Bari 2

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3
Q

Leflu inibe …

A

Di-hidro orato desidrogenase e leva a depleção da pirimidina intracelular - reduz síntese de RNA

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4
Q

Inibição da calcineurina leva …

A

Bloqueio da síntese de de IL2 por linfócitos T

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5
Q

Metotrexato inibie síntese …

A

Das purinas

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Biologicos (2 decks)

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