DM, HTN, Lipid drug names Flashcards
1
Q
Metformin
A
Glucophage 500mg qd/ bid, or 850mg qd with meals
2
Q
Metformin
A
Riomet 500mg qd/ bid, or 850mg qd with meals
3
Q
Metformin
A
Fortamet 500mg qd/ bid, or 850mg qd with meals
4
Q
Metformin
A
Glumetza 500mg qd/ bid, or 850mg qd with meals
5
Q
Glyburide
A
Diabeta 1.25; 2.5; 5 mg tab.
1.25- 20mg/day divided 1-2 doses w meals.
6
Q
Glyburide
A
Micronase 1.25; 2.5; 5 mg tab.
1.25- 20mg/day divided 1-2 doses w meals.
7
Q
Glipizide
A
Glucotrol 5; 10mg tab; or 2.5; 5; 10mg XL tab.
regular: 5- 40mg/day in 1-2 doses; and 30 min bf meals. For XL tab: 2.5-20mg/day take w breakfast.
8
Q
Glimepiride
A
Amaryl 1; 2; 4mg tab.
1-8mg once daily w meal.
9
Q
Glyburide+Metformin
A
Glucovance
10
Q
Glipizide+ Metformin
A
Metaglip
11
Q
Pioglitazon
A
Actos 15; 30; 45 mg tab
Start 15- 30mg qd
12
Q
Rosiglitazone
A
Avandia 2; 4; 8mg tab
Start at 4mg qd
13
Q
Nateglinide
A
Starlix 60; 120 mg tab
Start 60 mg TID w meals
(max 360mg/d)
14
Q
Repaglinide
A
Prandin 0.5; 1; 2 mg tab
Start 0.5 mg TID w meals
(max 16 mg/d)
15
Q
Acarbose
A
Precose 25; 50; 100 mg tab
25mg TID w 1st bite of each meal (max 300mg/day)
For <60kg, max 150mg/d.
16
Q
Miglitol
A
Glycet 25; 50; 100 mg tab
17
Q
Exenatide
A
Byetta 5; 10mcg. SQ BID x 1 month. Short-acting.
Within 60min before meal.
18
Q
Liraglutide
A
Victoza for DM/
Saxenda for weight loss
0.6; 1.2; 1.8mg SQ QD x1week.
Inject same time each day regardless meals. Long acting
19
Q
Exenatide ER
A
Bydureon 2 mg SQ q7d regardless meals. Long acting
20
Q
Abiglutide
A
Tanzeum 30; 50mg SC once weekly. Long acting
21
Q
Dulaglutide
A
Trulicity 0.75; 1.5mg SC once weekly. Long acting.
22
Q
Lixisenatide
A
Adlyxin 10; 20mcg SQ qd x14d. Short-acting
23
Q
Sitagliptin
A
Januvia 25;50; 100mg tab w or w/o food.
- CrCL (30, 50): 50mg QD
- CrCL<30: 25mg QD
- Not use for severe liver impair
24
Q
Saxagliptin
A
Onglyza 2.5; 5 mg tab w or w/o food. -CrCL<50: 2.5mg QD. - No adjustment for liver impair. - Co-administer w 3A4 Inhibitors (ketoconazole, clarithromycin, HIV drug …vir) => 2.5mg QD
25
Linagliptin
Tradjenta 5mg tab QD w/wo food.
| No adjustment for renal/ liver.
26
Alogliptin
Nesina 6.25; 12.5; 25mg tab QD w/wo food.
- CrCL (30, 60): 12.5mg
- CrCL<30: 6.25mg
- Not use if liver impair.
27
Januvia+ Metformin
Janumet
28
Canagliflozin
```
Invokana 100; 300mg QD
CrCL>60: 300mg
CrCL (45, 60): 100
CrCL<45: Avoid.
Take before morning meal.
```
29
Dapagliflozin
Farxiga 5; 10mg tab QD w/wo food.
| -CrCL<60: Not recommende
30
Empagliflozin
Jardiance 10; 25 mg tab
start 10mg QD w/wo food.
DDI w diuretics.
31
Ertugliflozin
Steglatro 5; 15 mg tab
32
Pramlintide
Symlin For T1DM:
| Start 15mcg before major meals TID. If tolerance, titrate by 15 to 30-60mcg TID.
33
Regular insulin
Novolin R, Humulin R
30’ before meal
No Rx
34
Lispro
```
Humalog
15’ before meal
With meal
20 ‘ after meal
Rx only
```
35
Aspart
```
Novolog
15’ before meal
With meal
20 ‘ after meal
Rx only
```
36
Lispro
```
Admelog
15’ before meal
With meal
20 ‘ after meal
Rx only
```
37
Aspart
```
Fiasp
15’ before meal
With meal
20 ‘ after meal
Rx only
```
38
Glulisine
```
Apidra
15’ before meal
With meal
20 ‘ after meal
Rx only
```
39
Oral inhaled
Afrezza
40
NPH
Novolin N
BID
Non Rx
Cloudy
41
NPH
Humulin N
BID
Non Rx
Cloudy
42
Glargine
Basalar
QD-BID
CANNOT MIX W ANY
43
Glargine
Lantus
QD-BID
CANNOT MIX W ANY
44
Glargine
Toujeo
QD-BID
CANNOT MIX W ANY
45
Detemir
Levemir
BID – Dose dependence
CANNOT MIX W ANY
46
Degludec
Tresiba
| QD
47
Degludec
Ryzodeg
48
Rosuvastatin
Crestor
49
Atorvastatin
Lipitor
50
Simvastatin
Zocor
51
Lovastatin
Mevacor
52
Pravastatin
Pravachol
53
Fluvastatin
Lescol XL
54
Pitavastatin
Livalo
55
Ezetimibe
Zetia 10mg PO QD w/wo food
56
Cholestyramine
Questran
57
Colestipol
Colestid
58
Colesevelam
WelChol
59
Ezetimibe+ Simvastatin
Vytorin
60
Praluent
Alirocumab 75mg SC q2wks; or 300mg SC q4wks.
61
Repatha
Evolocumab 140mg SC q2wks
62
Juxtapid
Lomitapide
63
Gemfibrozil
Lopid
64
Fenofibrate
Tricor
65
Fenofibrate
Antara
66
Fenofibrate
Fenoglide
67
Fenofibrate
Fibricor
68
Fenofibrate
Lipofen
69
Fenofibrate
Triglide
70
Fenofibrate
Trilipix
71
Fish oil Rx (Omega 3)
Lovaza
72
Icosapent Ethyl (Fish oil Rx)
Vascepa
73
Niacin ER
Niaspan
74
Chlorthalidone
Thalitone 25-100 mg po qd (100)
75
Hydrochlorothiazide (HCTZ)
HydroDiuril 12.5- 50mg po qd (50)
76
Indapamide
Lozol
77
Metolazone
Zaroxolyn
78
Bumetanide
Bumex
79
Ethacrynic acid
Edecrin 50-200 mg po qd/bid (400)
80
Furosemide
Lasix 20-40 mg po bid (160)
81
Torsemide
Demadex
82
Amiloride
Midamor
83
Triamterene
Dyrenium
84
Eplerenone
Inspra 50 mg po qd/bid (100)
85
Spironolactone
Aldactone 25-100 mg po qd/bid (100)
86
Benazepril
Lotensin 10-40 mg QD-BID (40)
87
Captopril
Capoten
88
Enalapril
Vasotec 2.5-40mgQD-BID(40)
89
Fosinopril
Monopril 10-40 mg daily (40)
90
Lisinopril
Zestril 10-40 mg daily (40)
91
Lisinopril
Prinivil 10-40 mg daily (40)
92
Perindopril
Aceon 4-8mgQD-BID(16)
93
Quinapril
Accupril
94
Ramipril
Altace 2.5-10mgQD-BID(20)
95
Trandolapril
Mavik
96
Moexipril
Univasc 7.5-15 mg QD-BID (30)
97
Azilsartan
Edarbi
98
Candesartan
Atacand
99
Eprosartan
Teveten
100
Irbesartan
Avapro
101
Losartan
Cozaar 25-100 mg po QD-BID (100)
102
Olmesartan
Benicar
103
Telmisartan
Micardis
104
Valsartan
Diovan 80-320 mg I po daily (320)
105
Amlodipine
Norvasc 2.5-10 mg I po daily (10)
106
Felodipine
Plendil 5-20 mg I po daily (20)
107
Isradipine
DynaCirc
108
Isradipine SR
DynaCirc SR
109
Nicardipine sustained-release
Cardene SR
110
Nifedipine long-acting
Adalat CC 30- 90 mg I po daily (180)
111
Nifedipine long-acting
Procardia XL 30- 90 mg I po daily (180)
112
Nisoldipine
Sular
113
Diltiazem SR 90-180 mg
Cardizem SR
114
Diltiazem SR 120-480mg
Cardizem CD, Cartia XT, Dilacor XR, Diltia XT, Tiazac, Taztia XT
115
Diltiazem ER
Cardizem LA
116
Verapamil SR
Calan SR, Isoptin SR, Verelan
117
Verapamil controlled-onset, ER
Covera HS
118
Verapamil chronotherapeutic oral drug absorption system
Verelan PM
119
Atenolol
Tenormin 25-100 mg I po daily (100)
120
Betaxolol
Kerlone
121
Bisoprolol
Zebeta
122
Metoprolol
Lopressor 25-100mg po BID (200)
123
Metoprolol extended release
Toprol XL 50-200 mg I po daily (200)
124
Nebivolol
Bystolic
125
Nadolol
Corgard
126
Propranolol
Inderal 40-160 mg I po BID (320)
127
Propranolol long-acting
Inderal LA 80- 160 mg I po daily (160)
128
Propranolol long-acting
InnoPran XL 80- 160 mg I po daily (160)
129
Timolol
Blocadren
130
Acebutolol
Sectral
131
Penbutolol
Levatol
132
Pindolol
Visken
133
Doxazosin
Cardura
134
Prazosin
Minipress
135
Terazosin
Hytrin
136
Clonidine
Catapres
137
Clonidine patch
Catapres-TTS
138
Methyldopa
Aldomet
139
Hydralazine
Apresoline 10-50 mg I po TID-QID (200)
140
Minoxidil
Loniten
141
Aliskiren
Tekturna
142
HTN urgency
Oral agents:
Captopril 25-50 mg q1-2h
Clonidine 0.2 mg qh up to 0.7 mg
Labetalol 200-400 mg q2-3h
143
HTN emergency
Parenteral agents:
- DHPCCB: Nicardipine, Clevidipine,
- Vasodilators: Nitroprusside, Nitroglycerin, Hydralazine,
- Adrenergic agents: Esmolol, Labetalol, Phentolamine,
- Dopamine R agonist: Fenoldopam.
- ACEI: Enaliprilat.
144
HTN emergency- Nicardipine
Cardene IV
CI: aortic stenosis.
Elderly: No dose adjustment.
145
HTN emergency- Clevidipine
Cleviprex.
Max duration 72 hrs.
CI: soybean, eggs allergy, pancreatitis.
Elderly: low-end dosing.
146
HTN emergency- Nitroprusside
CI: renal patients
Elderly: lower dosing.
Tolerance and cyanide toxicity if long use.
147
HTN emergency-Nitroglycerin
For acute coronary syndromes.
148
HTN emergency- Hydralazine
for preeclampsia/eclampsia.
| can use for pregnant women with BP 202/140
149
HTN emergency- Esmolol
Beta 1 R agonist
CI: concurrent BB therapy, bradycardia, decompensated HF.
For aortic dissection.
150
HTN emergency- Labetalol
Alpha1, beta1, alpha 2 antagonist.
CI: COPD, 2nd &3rd degree heart block, bradycardia.
-can worsen HF.
-For aortic dissection, preeclampsia/eclampsia.
151
HTN emergency- Phentolamine
for catecholamine excess
152
HTN emergency- Fenoldopam
CI: glaucoma, intracranial pressure, or sulfite allergy.
| -For acute renal failure .
153
HTN emergency- Enaliprilat
CI: pregnancy, acute MI, and bilateral renal artery stenosis .
Slow onset.
154
HTN in African American
1st line: Thiazide diuretics
| 2nd line: DHP CCB
155
HTN in pregnancy
Diuretic cat B, ACE/ARB cat X, CCB cat C, BB cat C, Aliskiren cat D.
- Treat chronic HTN: 1st: methyldopa 250-500 mg PO qd/bid (max 1000), 2nd: labetalol, or 3rd: nifedipine.
- Treat pre-eclampsia: (after 20 wks= 2nd trimester; signs: HTN+Proteinuria) => 1st line: IV Hydralazine; 2nd line: Labetalol.
156
HTN in elderly
1st line: Thiazide 12.5mg PO qd.
2nd line: ACEI (lowest dose)
CI: Alpha 1 antagonist (_zosin, Tamsulosin), and centrally acting alpha 2 agonist (Methyldopa, clonidine, Guanabenz, Guanfacine).
=> ortho. hypotension.
157
Isolated Systolic HTN
(SBP>=160 and DBP=<90)
1st: Thiazide 12.5mg PO qd.
2nd: DHP CCB low doses.
158
HTN in Children and Adolescents
Non-pharm is primary therapy.
Rx: Diuretics, beta blockers, ACEI.
CI in sexually active teenage girls: ACEI/ARB.
159
HTN in Men with BPH
1st: use med for BPH.
2nd: Alpha 1 antagonists (_zosin, Tamsulosin)
