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Mod 3 > DM drugs > Flashcards

DM drugs Flashcards

1
Q

Biguanide

A

Metformin

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2
Q

Metformin SOA

A

Liver

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3
Q

When to not use metformin

A

GFR <30 or don’t start if GFR is 30-45, or planning metabolic surgery

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4
Q

Sulfonyureas

A

“ide”

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5
Q

Sulfonyureas SOA

A

Pancreas (requires functioning beta cells to work)

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6
Q

Sulfonyureas warnings

A

Hypoglycemia- Caution with elderly,
Don’t give if allergic to Sulfa
Don’t give in pregnancy
Low cost- Weight gain

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7
Q

TZDs

A

“Gliazones”

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8
Q

TZDs SOA

A

Nucleus

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9
Q

TZDs SE

A

Live toxicity, Risk of bone fx related to bone loss

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10
Q

TZDs warnings

A

No hypoglycemia
BLACK BOX- CHF- due to SE of fluid retention

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11
Q

DPP4

A

“Gliptins”

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12
Q

DPP4- SOA

A

Pancreas

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13
Q

DPP4 SE

A

pancreatitis- GI symptoms- Joint pains

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14
Q

DPP4 Warnings

A

High cost- neutral weight loss
NO hypoglycemia
Don’t use with GLP-1

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15
Q

GLP-1

A

“Tides”

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16
Q

GLP-1 SOA

A

Pancreas

17
Q

GLP-1 MOA

A

Delays gastic emptying, improves postprandial glucose

18
Q

GLP-1 SE

A

GI upset, inj site rx, pancreatitis

19
Q

GLP-1 Warnings

A

High cost- weight lost
Dont use with DPP4
BLACK BOX- Thyroid CA

20
Q

SGLT2

A

“Flozins”

21
Q

SGLT2 SOA

A

Proximal Renal tubules- Kidneys

22
Q

SGLT2 MOA

A

increase renal glucose excretions- Glycosuria

23
Q

SGLT2 SE

A

GU infections, UTI, peeing more- Hypotension- increase risk for falls, increase risk for bone fx
Fournier’s

24
Q

SGLT2 Warnings

A

High cost- Wight lost
No hypoglycemia
BLACK BOX- Risk of amputation

25
Q

What drug to use with ASCVD

A

GLP-1 or SGLT2

26
Q

What drug to use with CHF?

A

SGLT2

27
Q

What drug to use with CKD?

A

SGLT2 or GLP-1

28
Q

What drug to use to min hypoglycemia evernts?

A

GLP-1, SGLT2, DPP4, TZD

29
Q

What drugs are most cost effective?

A

SU or TZD

30
Q

What drugs will help loss weight?

A

GLP-1 or SGLT2

Mod 3 (5 decks)

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