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Self NAPLEX > DM > Flashcards

DM Flashcards

1
Q

sitagliptin phosphate

A

Januvia

DPP4 Inhibitor (stop met of GLP-1)

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2
Q

saxagliptin

A

Onglyza

DPP4 Inhibitor (Stop met of GLP-1)

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3
Q

linagliptin

A

Tradjenta

DPP4 Inhibitor (stop met of GLP-1)

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4
Q

alogliptin

A

Nesina

DPP4 Inhibitor (stop met of GLP-1)

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5
Q

exenatide

A

Byetta or Bydureon (ER)

GLP-1 AGonist
Weight loss

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6
Q

liraglutide

A

Victoza

GLP-1 AGonist
Weight loss

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7
Q

dulaglutide

A

Trulicity

GLP-1 AGonist
Weight loss

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8
Q

albiglutide

A

Tanzeum

GLP-1 AGonist
Weight loss

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9
Q

lixisenatide

A

Adlyxin

GLP-1 AGonist
Weight loss

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10
Q

canagliflozin

A

Invokana

SLGT2 Inhibitor (pee glu)

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11
Q

dapagliflozin

A

Farxiga

SLGT2 Inhibitor (pee glu)

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12
Q

empagliflozin

A

Jardiance

SLGT2 Inhibitor (pee out glu)

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13
Q

bromocriptine

A

Cycloset

Dopamine AGonist

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14
Q

DPP4 Inhibitors MOA

A

Stop metabolism of GLP-1

Weight neutral

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15
Q

DPP4 Inhibitors Brands

A

Januvia - sitagliptin phosphate
Onglyza - saxagliptin
Nesina - alogliptin
Tradjenta - linagliptin

DPP4 Inhibitors (stop met of GLP-1)
Weight neutral
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16
Q

GLP-1 AGonist Brands

A 
ATT By Victoria (the tides = loss)
Byetta and Bydureon  - exenatide
Victoza        - liraglutide 
Trulicity       - dulaglutide 
Tanzeum     - albiglutide
Adlyxin        - lixisenatide

GLP-1 AGonist
Weight loss

17
Q

SLGT2 Inhibitors Brands

A

Invokana - canagliflozen
Farxiga - dapagliflozen
Jardiance - empagliflozen

Pee out glucose - FLOWzen

18
Q

glimepiride

A

Amaryl

Safe in renal failure (100% liver)
- reduce dose
Sulfonylurea
Secrete insulin

19
Q

glipizide

A

Glucotrol

DOC in RENAL FAILURE (no dose adj)
EMPTY STOMACH (30 min before meal)

Sulfonylurea
Secrete insulin

20
Q

glyburide

A

Micronase - DiaBeta
Micronized - Glynase

Sulfonylurea
Secrets insulin

21
Q

List Biguanides Brands

A 
Metformin brands:
Glucophage - 2550/d
Glucophage XR - 2500/d
Fortamet ER - 2500/d - full glass water
Glumetza ER - 2000/d

QD with evening meal

22
Q

Biguanide Combos

A 
Glucovance (glyburide/met)
Avandamet (rosiglitazone/M)
Jentaduo (linagliptin/M)
Actoplus Met (pioglitazone/M)
Prandimet (repaglinide/M)
Kombiglyze XR (saxagliptin/M)
Kazano (alogliptin/M)
Invokamet (canagliflozen/M)
Xigduo (dapagliflozen/M)
Synjardy (empagliglozen/M)
23
Q

Thiazolidinedione Brands

A

Avandia - rosiglitazone
Actos - pioglitazone

XXX CHF II/III
Work on receptors

24
Q

Alpha-Glucosidase Inhibitor Brands

A

Precose - acarbose
Glyset- miglitol

Bind sucrose
Lower post prandial hyperglycemia

25
Q

acarbose

A

Precose

Alpha-glycosidase Inhibitor
Bind sucrose
Lower post prandial hyperglycemia

26
Q

miglitol

A

Glyset

Alpha-Glucosidase Inhibitor
Bind sucrose
Lower post prandial hyperglycemia

27
Q

Meglitinides Brands

A

Prandin - repaglinide
Starlix - nateglinide

Secrete insulin (like sulfonylureas)

28
Q

repaglinide

A

Prandin

Meglitinide
Secrete insulin (like sulfonylureas)
29
Q

nateglinide

A

Starlix

Meglitinide 
Secrete insulin (like sulfonylureas)
30
Q

Biguanide MOA

A

Metformin
Decrease hepatic glucose production
Stim glycolysis in liver
Improves insulin sensitivity

Does NOT cause hypoglycemia
Does NOT cause weight gain (weight loss)
Favorable lipid effects

31
Q

rosiglitazone

A

Avandia

Thiazolidinedione
XXX - CHF
Work on receptors

32
Q

pioglitazone

A

Actos

Thiazolidinedione
XXX CHF
Work on receptors

33
Q

GLP-1 Agonists MOA

A

Increase insulin production
Stop liver from making too much glu
Reduce appetite - weight loss

34
Q

Any med that increases insulin secretion can…?

A

Cause hypoglycemia

Examples:
Insulin
Sulfonylurea
Most except metformin

Self NAPLEX (1 decks)

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