DM Flashcards
sitagliptin phosphate
Januvia
DPP4 Inhibitor (stop met of GLP-1)
saxagliptin
Onglyza
DPP4 Inhibitor (Stop met of GLP-1)
linagliptin
Tradjenta
DPP4 Inhibitor (stop met of GLP-1)
alogliptin
Nesina
DPP4 Inhibitor (stop met of GLP-1)
exenatide
Byetta or Bydureon (ER)
GLP-1 AGonist
Weight loss
liraglutide
Victoza
GLP-1 AGonist
Weight loss
dulaglutide
Trulicity
GLP-1 AGonist
Weight loss
albiglutide
Tanzeum
GLP-1 AGonist
Weight loss
lixisenatide
Adlyxin
GLP-1 AGonist
Weight loss
canagliflozin
Invokana
SLGT2 Inhibitor (pee glu)
dapagliflozin
Farxiga
SLGT2 Inhibitor (pee glu)
empagliflozin
Jardiance
SLGT2 Inhibitor (pee out glu)
bromocriptine
Cycloset
Dopamine AGonist
DPP4 Inhibitors MOA
Stop metabolism of GLP-1
Weight neutral
DPP4 Inhibitors Brands
Januvia - sitagliptin phosphate
Onglyza - saxagliptin
Nesina - alogliptin
Tradjenta - linagliptin
DPP4 Inhibitors (stop met of GLP-1) Weight neutral
GLP-1 AGonist Brands
ATT By Victoria (the tides = loss) Byetta and Bydureon - exenatide Victoza - liraglutide Trulicity - dulaglutide Tanzeum - albiglutide Adlyxin - lixisenatide
GLP-1 AGonist
Weight loss
SLGT2 Inhibitors Brands
Invokana - canagliflozen
Farxiga - dapagliflozen
Jardiance - empagliflozen
Pee out glucose - FLOWzen
glimepiride
Amaryl
Safe in renal failure (100% liver)
- reduce dose
Sulfonylurea
Secrete insulin
glipizide
Glucotrol
DOC in RENAL FAILURE (no dose adj) EMPTY STOMACH (30 min before meal)
Sulfonylurea
Secrete insulin
glyburide
Micronase - DiaBeta
Micronized - Glynase
Sulfonylurea
Secrets insulin
List Biguanides Brands
Metformin brands: Glucophage - 2550/d Glucophage XR - 2500/d Fortamet ER - 2500/d - full glass water Glumetza ER - 2000/d
QD with evening meal
Biguanide Combos
Glucovance (glyburide/met) Avandamet (rosiglitazone/M) Jentaduo (linagliptin/M) Actoplus Met (pioglitazone/M) Prandimet (repaglinide/M) Kombiglyze XR (saxagliptin/M) Kazano (alogliptin/M) Invokamet (canagliflozen/M) Xigduo (dapagliflozen/M) Synjardy (empagliglozen/M)
Thiazolidinedione Brands
Avandia - rosiglitazone
Actos - pioglitazone
XXX CHF II/III
Work on receptors
Alpha-Glucosidase Inhibitor Brands
Precose - acarbose
Glyset- miglitol
Bind sucrose
Lower post prandial hyperglycemia
acarbose
Precose
Alpha-glycosidase Inhibitor
Bind sucrose
Lower post prandial hyperglycemia
miglitol
Glyset
Alpha-Glucosidase Inhibitor
Bind sucrose
Lower post prandial hyperglycemia
Meglitinides Brands
Prandin - repaglinide
Starlix - nateglinide
Secrete insulin (like sulfonylureas)
repaglinide
Prandin
Meglitinide Secrete insulin (like sulfonylureas)
nateglinide
Starlix
Meglitinide Secrete insulin (like sulfonylureas)
Biguanide MOA
Metformin
Decrease hepatic glucose production
Stim glycolysis in liver
Improves insulin sensitivity
Does NOT cause hypoglycemia
Does NOT cause weight gain (weight loss)
Favorable lipid effects
rosiglitazone
Avandia
Thiazolidinedione
XXX - CHF
Work on receptors
pioglitazone
Actos
Thiazolidinedione
XXX CHF
Work on receptors
GLP-1 Agonists MOA
Increase insulin production
Stop liver from making too much glu
Reduce appetite - weight loss
Any med that increases insulin secretion can…?
Cause hypoglycemia
Examples:
Insulin
Sulfonylurea
Most except metformin
