DM Flashcards

1
Q

Secretagogos (2)

A

Sulfonilureias e Glinidas

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2
Q

Classes de drogas que atuam no mecanismo das incretinas (2)

A

Análogos GLP-1 e Inibidoras DPP-4

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3
Q

Aumentam sensibilidade à insulina

A

Glitazonas (sens periférica) e Biguanidas (metformina)

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4
Q

Promovem perda urinária de glicose (1)

A

iSGLT2

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5
Q

Quais drogas provocam ganho ponderal e hipoglicemia?

A

Sulfonilureias e glinidas

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6
Q

EA das glitazonas

A

Congestão

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7
Q

ClCr < 45 o que fazer com metformina?

A

Dividir a dose em dois

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8
Q

EA de metformina que não seja GI (3)?

A
  1. Acidose láctica
  2. Deficiência de B12
  3. Insuficiência renal
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9
Q

EA dos iSGLT2 (3)

A

hipovolemia
cetoacidose euglicemica
itu/candidíase

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10
Q

Critério pra tto de pré-DM

A

IMC > 35
Idade < 60 anos
Mulher com hx de DMG
Síndrome metabólica com HAS
GJ > 110

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11
Q

Insulinas ultrarrápidas (3)

A

Abaixa a linda glicose
Aspart Lispro Glulisina

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12
Q

Insulinas de longa (3)

A

Detemir
Glargina
Degludeca

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13
Q

Qual a melhor medicação pensando em DCV?

A

iSGLT2

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14
Q

Critério de pré-DM

A

Hba1c 5,7%
GJ 100-125
TOTG 140-199

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15
Q

Em que situações as glitazonas estão contraindicadas?

A
  • insuficiência hepática
  • insuficiência cardíaca classe III ou IV
  • gestantes
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16
Q

Qual das classes de hipoglicemiantes aumenta o risco de fraturas ósseas?

A

Glitazonas