DM

Question 1

Hormone that Increases in DM

Answer 1

Glucagon
Epinephrine
Cortisol
hGH

Question 2

Type of DM characterized by being Autoimmune
–Selective destruction of βcells by lymphocytes
– Circulation antibodies

Answer 2

Type 1

Question 3

Viral risks factors for DM1

Answer 3

Coxsackie
Pox Virus
Rubella

Question 4

Nutrimental risk factors for DM1

Answer 4

Cow Milk

Question 5

DM2 can be both by ____ or ____

Answer 5

Insulin action deficiency 
Insulin deficiency (Beta cell destruction)

Question 6

In. DM2, insulin action deficiency produces _____ production by the liver and _____ glucosee utilization by muscle or adipocytes

Answer 6

More glucose

Less

Question 7

a lot of glucose in the blood produces glucose ____

Answer 7

Secretion in urine

Question 8

As there is no glucose uptake, cells such as miocytes or adipocytes, go to the ___ pathway, and then ____

Answer 8

proteolisis/lipolisis

Gluconeogénesis

Question 9

Familiar background is related in DM type ___

Answer 9

DM2

Question 10

Obesity is not common in DM type ___

Answer 10

DM1

Question 11

3 pls in diabetes stand for ___

Answer 11

Polydipsia, Polyfagi, polyuria

Question 12

Acute complications od DM

Answer 12

Hypoglicemia, Ketoacidosis, Non Keto hyperosmolar staate

Question 13

Chronic complications of DM divide into

Answer 13

Macrovascular

Microvascular

Question 14

Crónica macrovascular complications of DM

Answer 14

Coronary disease
Cardiovascular disease
Periphereal vascular disease

Question 15

crónica microvascular complications of DM

Answer 15

Retinopathy
Neuropathy
Nefropathy

Question 16

Diabetic level of glucose while fasting

Answer 16

> 126mg/dl

Question 17

Diabetic level of glucose postprandial

Answer 17

> 200mg/dl

Question 18

Diabetic HbA1C levels

Answer 18

> 6.5 mg(dl

(5.6 sano)

Question 19

Sulfonylureas such as Glibenclamide is not indicated in Px with

Answer 19

Kidney Failure

Question 20

Biguanids such as Metformin is not indicated in

Answer 20

Kidney or liver failure, alcoholismo, lactic acidosis

Question 21

They produce insulin secretion by K channel, but you gain weight and may produce hypoglicemia

Answer 21

Sulfonylureas

Question 22

Produces decreased hepatic production of glucose and increases muscle sensitivity to it, as lowering GI glucose absorption

Answer 22

Metformin

Question 23

Metformin side effect is

Answer 23

Acidosis

Question 24

It binds to peroxisome proliferative protein increasing insulin sensitivity in liver and muscle

Answer 24

Thiazolidinediones

Question 25

They inhibit brush border enzymes but can cause diarreah, flatulence

Answer 25

A-glucosiddase inhibidos

Question 26

Increase incretine levels which disminishes glucagon release and increases insulin realease
Diminishes gastric emptying

Answer 26

May produce headache

DPP-4

Question 27

may produce pancreatitis, vomito an diarrhea
• Disminish gastric emptying
Increase insulin release Supress glucagon secretion

Answer 27

glp-1 aGONISTAAS

Question 28

block glucose reabsorption from kidneys, increases urine secretion of it

Answer 28

Inh SGLT-2

Question 29

iN THERAPY, the glucose goal for the diabetic is ___ while fasting, ___ after meal and ___ HbA1C

Answer 29

0

80-110; <140; <7%

Question 30

The non vascular chronic complications for DM

Answer 30

Gastroparesis
Sexual dysfunction
Skin dehydration

Question 31

These are complications of DM called____
• • •
Burning pain in both feet (socks) and hands (gloves) Paresthesias, disesthesias
Fine stinging paresthesias, electrical paroxisms Allodynia to mechanical touch and thermal heat

Answer 31

Neuropathy

Question 32

Pie diabético in inglich

Answer 32

Charcot foot