Diverticular Disease Flashcards
What is a diverticulum?
An outpouching of the bowel wall most commonly found in the sigmoid colon.
4 types of manifestations of diverticulum.
Diverticulosis = presence of diverticula (asymptomatic and found on imaging)
Diverticular disease (symptomatic)
Diverticulitis (symptomatic + inflammation)
Diverticular bleed (diverticulum erodes into a vessel and causes large volumes of painless bleeds)
Epidemiology
Diverticulosis = 50% of >50y 70% of >80y
Only 25% of these cases become symptomatic
M>F
Pathophysiology
Aging bowel = becomes weakened
Movement of stool -> increase in luminal pressure
Leads to outpouching of the mucosa through the weaker areas of the bowel.
Bacteria can overgrow in the outpouchings, especially when there is an obstruction.
This can also leads to perforation and peritonitis sepsis in severe cases.
What can happen in chronic cases of diverticular disease?
Fistulae can form
Colovesical or colovaginal
What are the weaker areas of the bowel wall?
The junctions of the trinagular muscle sheets
Blood vessels penetrate to supply the bowel wall
What can diverticulitis be classified as?
Simple
Complicated
Explain simple diverticulitis
Inflammation without abscess or free perforation
Explain complicated diverticulitis
Abscess or free perforation
Risk factors
Age
Low dietary fibre intake
Obesity
Smoking
FH
NSAIDs
Clinical features of diverticular disease
Intermittent lower abdo pain that is typically colicky in nature
May be relieved by defecation
Altered bowel habits
Nausea
Flatulence
No systemic features
Clinical features of acute diverticulitis
Acute abdominal pain that is usually sharp in nature and localised in the LIF
Worsened pain on movement
Examination findings of acute diverticulitis
Localised tenderness
Systemic upset
Decreased appetite
Pyrexia
Nausea
Presentation of perforated diverticulum.
Signs of localised peritonism or generalised peritonitis
They might be extremely unwell and it can be fatal
When might the symptoms of diverticulitis and diverticular disease be masked?
In patients that are taking corticosteroids or immunosuppressants.
In patients with a redundant sigmoid colon the pain may be found in the right lower quadrant or suprapubic area.