Diverticular disease Flashcards
What is a diverticulum?
- Outpouching of the bowel wall
- Commonly in the sigmoid colon
- More common in men in devloped countries
What are the manifestations of diverticular disease?
- Diverticulosis - presence of diverticula
- Diverticular disease - symptomatic diverticula
- Diverticulitis - inflammation of the diverticula
- Diverticular bleed - the diverticulum erodes into a vessel and causes painless bleed
Describe the pathophysiology of diveriticular disease?
- Ageing bowel becomes weakened over time
- Movement of stool causes increased luminal pressure
- Outpouching of mucosa occurs in areas of weaker bowel wall
- Bacteria overgrowth at outpoutching causes diverticulitis (can perforate)
Describe the classification of divertiulitis?
- Simple
- Complicated
- Abscess presence, fistual formation, stricutre, perforation
Risk factors for diverticular disease?
- Low dietary fibre intake
- Obesity (younger patients)
- Smoking
- Family history
- NSAID use
What are the clinical features of diverticular disease?
- Mostly asymptomatic found incidentally on colonscopy/CT
- Diverticular pain
- Intermittent lower abdominal pain
- Colicky in nature, relieved by defaecation
- Associated nausea and flatulence
How will diverticulitis present?
- Acute abdominal pain
- Sharp in nature
- Normally localised in left iliac fossa pain
- Worsened by movement
- Features of systemic upset
- Decreased appetite
- Pyrexia
- Nausea
How will a perforated diverticulum present?
- Signs of localised peritonism or generalised peritonitis
- Patients are frequently unwell
What can mask the symptoms of diverticulitis?
- Corticosteroids
- Immunosuppressants
Complications of divertiular disease?
- Pericolic abscess
- antibiotics and bowel rest -> CT guided drainage
- Fistula formation
- Bowel obstruction
- secondary to stricture formation
- managed through stenting or bowel resection
What are the common fistula subtypes?
- Colovesical fistula
- Pneumoturia (gas in urine), faecal matter in urine, recurrent UTIs
- Colovaginal fistula
- Copious vaginal discharge, recurrent vaginal infections
- **Both require surgical resection and repair
Differentials for diverticular disease?
- Inflammatory bowel disease
- Bowel cancer
- Mesenteric ischaemia, gynaecological causes, renal stones
What investigations should be performed in someone with suspected diverticular disease?
- FBC, CRP, faecal calprotectin
- Group and save, venous blood gas, urine dipstick
- Imaging:
- CT abdomen pelvis
- ***Colonscopy should not be performed in causes of suspected diverticulitis due to increased risk of perforation
What signs on CT suggest a diagnosis of diverticulitis?
- Thickening of the colon wall
- Pericolonic fat stranding
- Abscesses
- Localised air bubbles
Describe the staging of Acute diverticulitis?
- Hinchley Classification
- Based on CT findings
- Aids clinical management
- Higher stages associated with higher morbidity/mortality