Diverticular Disease Flashcards
What is a GI diverticulum?
Outpockets of colonic muscosa/submucosa usually at sites of perforation by arteries. NOT INFLAMED
What is diverticular disease?
Divertuclum have become symptomatic
What is diverticulitis?
Inflammation and infection of diverticulum
What are the two main types of diveritculum?
Aquired
Congenital
What causes diverticulum?
UNKNOWN, SEVERAL THEORIES
- fibre deficiency
- change in strength of colonic wall w/ age/CT deficiencies
Describe the fibre deficiency theory
Lack of dietary fibre –> high intraluminal pressure –> mucosa herniates adjacent to perforating arteries
Describe the colonic wall theory
Change in strength of colonic wall due to
-age
-CT disorders
-collagen disorder
Weakened, increased risk of diverticulitis
What are the risk factors for diverticular disease?
>50 Low dietary fibre Obesity Smoking NSAIDs/Paracetamol Marfans, Ehler's-Danlos, PKD
Where do most diverticulum occur?
Sigmoid colon
-95% of complications here
In what less common places can diverticulum occur?
Right colon
Massive single diverticulum anywhere
What are the complications of diverticulosis?
Perforation Abscess formation Bleeding Fistula formation Intestinal obstruction Strictures
What are the symptoms/signs of diverticular disease?
Can be asymptomatic Left sided colic (relieved by defecation Altered bowel habit (blood/mucus) Nausea Flatulence Severe pain/constipation (if luminal narrowing)
What investigations are appropriate in suspected diverticular disease?
PR (pelvic abscess? colorectal cancer?)
Sigmoidoscopy/Colonoscopy
Barium enema
CT
Think about 2ww criteria- most patients will be referred on this
What is the 1st line medical management for diverticular disease?
Mebeverine
What is diverticulosis?
The presence of diverticula