Diversity, Classification And Variation Flashcards
What are gametes?
Sex cells
Gametes fuse together to form.x
A zygote.
Normal body cells have …
The diploid number of chromosomes - 2n
Each cell contains two of each chromosomes - one from mum and one from dad.
Gametes have …
A haploid number of chromosomes - only one copy of each chromosomes.
At fertailisation,
Two haploid cells fuse together to form the normal diploid number of chromosomes.
Meiosis
1) DNA unravels and replicates = two copies of each chromosome called chromatids.
2) DNA condensed to from double armed chromosomes each made from 2 sister chromatids joined by a centromere.
3) Meisois 1 - chromosomes arrange in homologous pairs and they’re separated halving the chromosome number
4) Meisois 2 - the pairs of sister chromatids that make up each chromosome are deprecated.
5) 4 haploid gamete cells are produced.
What happens during Meiosis 1?
Homologous pairs of chromosomes come together and pair up - chromatids twist around eachother and bits of chromatids swap over = different combos of alleles
2 events which leads to genetic variation during Meiosis:
- crossing over of chromatids
- independent segregation of chromosomes
Explain what happens during independent segregation:
When the homologous pairs are separated in the first division, it’s completly random which chromosomes from each pair ends up in which daughter cell - 4 daughter cells have diff combos of chromosomes.
Three differences between Mitosis and Meiosis:
Mitosis produces cells with same number of chromosomes as parent cell = Meiosis produces half.
Mitosis is genetically identical = meiosis is not.
Mitosis produces 2 daughter cells = meiosis produces 4
What is chromosome mutation?
When something goes wrong and the cells produced contain variations in the numbers of whole chromosomes of parts of chromosomes.
Chromosome mutations lead to…
Inherited conditions because the errors are present in the gametes.
One type of chromosome mutation:
Non-disjunction - failure of the chromosomes to seperate properly - DOWN’s SYNDROME.
Down’s syndrome is caused by…
A person having an extra copy of chromosome 21.
The resulting zygote has 3 copies of chromosome 21.
What are mutations?
Changes to the base sequence of DNA.
2 mutations:
Substitution
One base is substituted with another
Deletion
One base is deleted
Why do mutations affect a gene?
Because the order of DNA bases in a gene determines the other of amino acids in a particular protein - a change would change the sequence of amino acids it coded for and the protein.
Not all mutations affect the order of amino acids…
Because the degenerate nature of the genetic Code means that some amino acids are coded for by more than one DNA triplet.
Will deletion always lead to changes in the amino acid sequence?
Yes because the number of bases present will change which causes a shift in all the base triplets after it.
What do mutagenic agents do?
They increase the rate of mutation.
Examples of Mutagenic Agents:
UV radiation, ionising radiation etc.
What is Genetic Diversity?
Is the variety of different alleles of a genes in a species or population.
How can Genetic Diversity be increased? (2)
- mutations in the DNA.
- different alleles being introduced into a population because of migration - GENE FLOW.
What is a Genetic Bottleneck?
An event that causes a big reduction in a population.
It reduces the number of different alleles in the gene pool and so reduces Genetic Diversity.
What is the Founder Effect?
A type of Genetic Bottleneck.
What happens in the Founder Effect?
When just a few organisms from a population start a new colony and there are only a small number of different alleles in the initial gene pool.
The Founder Effect results in…
A higher incidence of genetic disease.
Describe Natural Selection:
Random mutations cause variation in a population of species. Species with the advantage are able to survive, reproduce and pass on their genes increasing the beneficial allele from generation to generation.