diuretics Flashcards
Where does sodium get reabsorbed in the nephron?
proximal convoluted tubules
ascending area of loop of henle
distal convoluted tubules (early and late)
Where does water get reabsorbed?
descending area of loop of henle
collecting duct
Why does water reabsorption require sodium?
is passive and requires the osmotic gradient established by sodium pumping
What drug acts on the ascending part of the loop?
frusemide
What drugs are used in the early part of the distal convoluted tubules?
“Thiazides”
hydrochlorothiazide
indapamide
What area does most of the sodium get regulated in the nephron?
late part of the distal convoluted tubule
What drug regulates the late distal convoluted tubule?
aldosterone
What are some aldosterone antagonists?
spironolactone
eplerenone
What is another sodium channel blocker in the late distal convoluted tubule?
amiloride