diuretics Flashcards

1
Q

Where does sodium get reabsorbed in the nephron?

A

proximal convoluted tubules
ascending area of loop of henle
distal convoluted tubules (early and late)

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2
Q

Where does water get reabsorbed?

A

descending area of loop of henle
collecting duct

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3
Q

Why does water reabsorption require sodium?

A

is passive and requires the osmotic gradient established by sodium pumping

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4
Q

What drug acts on the ascending part of the loop?

A

frusemide

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5
Q

What drugs are used in the early part of the distal convoluted tubules?

A

“Thiazides”
hydrochlorothiazide
indapamide

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6
Q

What area does most of the sodium get regulated in the nephron?

A

late part of the distal convoluted tubule

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7
Q

What drug regulates the late distal convoluted tubule?

A

aldosterone

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8
Q

What are some aldosterone antagonists?

A

spironolactone
eplerenone

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9
Q

What is another sodium channel blocker in the late distal convoluted tubule?

A

amiloride

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