Distribution Flashcards

1
Q

ABCB1 (p-glycoprotein)

A

amphipathic anions, nonconjugated

neutral or weakly basic lipophilic substrate

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2
Q

ABCC1-3

A

organic anions; glucuronides, sulfates, glutathione adducts, LTC4

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3
Q

ABCG2

A

substantial overlap in substrate specificity with ABCB1:

amphipathic anions, nonconjugated
neutral or weakly basic lipophilic substrate

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