Distribution Flashcards
1
Q
ABCB1 (p-glycoprotein)
A
amphipathic anions, nonconjugated
neutral or weakly basic lipophilic substrate
2
Q
ABCC1-3
A
organic anions; glucuronides, sulfates, glutathione adducts, LTC4
3
Q
ABCG2
A
substantial overlap in substrate specificity with ABCB1:
amphipathic anions, nonconjugated
neutral or weakly basic lipophilic substrate