Dissociation Curve

Question 1

What is Bohr effect?

Answer 1

Where O2 is bubbled through a known volume of blood for a specific time with a varying partial pressure of O2 and the more CO2 the higher the pp needs to be for attachment, shifting it to right, reducing affinity

Question 2

How is oxygen transported

Answer 2

By haemoglvoun creating oxyhaenoglibun
First attachment easiest
High partial pressure of O2, low pp if CO2 and a lower temp favoured attachment

Question 3

What are percentages of CO2 in body?

Answer 3

5% in solution of blood plasma
10% Congo es with amine groups of Hämoglobin
85% carried as hydrogen carbonate ions

Question 4

How is co2 transported in blood?

Answer 4

1. Diffuses into cytoplasm of RBC
2. Carbonic ahyedase catalyses conversion of CO2 and water into bicarbonate
3. Bicarbonate dissociates into H ions and hydrogen carbonate ions
4. Hydrogen carbonate diffuses into plasma and chloride ions diffuses into RBC to maintain electrical neutrality in chloride shift
5. Hydrogen ions attach to haeomogljbjn to make haemoglobinic acid and replaces oxygen
6. Oxygen diffuses out of RBC into tissues