Disorders of Osmoregulation Flashcards
osmolytes
reverse cell swelling
-without interfering with protein function
acute hyponatremia
cerebral edema
acute hypernatremia
cerebral shrinkage
hyponatremia
caused by:
- loss of sodium and potassium
- retention of ingested or infused water
frequently associated with inability to suppress secretion of ADH
CHF?
can lead to hyponatremia
- low cardiac output
- increased thirst
SIADH
syndrome of inappropriate ADH
-will lead to hyponatremia if associated with increased fluid intake
hypernatremia
prevented by ADH and thirst**
DDAVP
analog of ADH
addisons disease
decreased aldosterone secretion
-can lead to hyponatremia
treatment of hyponatremia
hypertonic solution too rapidly can result in demyelination
diabetes insipidus
lack of ADH
-central or nephrogenic
cell shrinkage
hypernatremia
cell swelling
hyponatremia
pressure natriuresis
increased BP leads to increased urinary volume excretion