DISORDERS OF LEUKOCYTES Flashcards
Causes of neutrophilia
acute bacterial infections
tissue necrosis
stress response
Causes of neutropenia
severe infections
bone marrow suppression
Toxic neutrophils
toxic granulation
döhle bodies
Causes of eosinophilia
parasitic infections
hypersensitivity reactions
Causes of eosinopenia
corticosteroid therapy
acute stress response
Causes of basophilia
allergic reactions
mast cells tumors
heartworm disease
Causes of basopenia
difficult to assess
stress-related
Causes of lymphocytosis
chronic antigenic stimulation
lymphocytic leukemia
Causes of lymphopenia
acute viral infections
immunosuppressive therapy
Causes of monocytosis
chronic infections
tissue necrosis
Causes of monocytopenia
rare, usually insignificant
severe bone marrow suppression
Common in bacterial infections, stress responses, and inflammatory diseases
Neutrophilia
Associated with parasitic infections, allergies, and hypersensitivity reactions
Eosinophilia
Occurs in chronic infections, leukemia, or immune responses
Lymphocytosis
Common in chronic bacterial infections and granulomatous infections
Monocytosis
Occurs due to infection, inflammation, stress, or neoplasia
Leukocytosis
Occurs due to bone marrow suppression, overwhelming infections, or viral diseases
Leukopenia
Occurs in viral infections, sepsis, bone marrow failure
Neutropenia
Seen in viral infections or stress
Lymphopenia
Rare but may occur in severe bone marrow suppression or steroid therapy
monocytopenia
Occurs in response to anemia, particularly hemolytic anemias, hemorrhage, or hypoxa-induced erythropoietin stimulation
Erythroid hyperplasia
Triggered by chronic bacterial infections, tissue necrosis, and inflammatory conditions that demand more neutrophils and monocytes
Myeloid hyperplasia
Results from platelet consumption in conditions like DIC or immune-mediated thrombocytopenia
Megakaryocytic hyperplasia
Occurs due to inflammation, congestion, neoplasia, or immune stimulation
Splenomegaly
Most common malignant splenic tumor in dogs
Hemangiosarcoma
Neoplastic proliferation of lymphocytes in the spleen
Lymphoma
Benign proliferative lesions in dog
Nodular hyperplasia
Spleen pathology that is common in large breed dogs and deep-chested breeds
Splenic torsion
Amyloid deposits in splenic follicles, appearing as gray, translucent nodules
Sago spleen
Diffuse amyloid deposition, giving the spleen a waxy, enlarged appearance
Lardaceous spleen
detects thymic masses, mediastinal widening, and pleural effusion
Thoracic Radiography
Helps differentiate thymomas from thymic lymphomas
Fine needle aspiration and cytology
Essential for definitive tumor classification and staging
Histopathology
Required for cats and cattle with suspected thymic lymphoma
Serology
