Disorders of appetitie Flashcards
What is excessive thirst called?
Polydipsia
What is absence of thirst called?
Adipsia
What is absence of hunger called?
Anorexia
What is obesity?
Excessive accumulation of fat
What is the hormone responsible for the regulation of osmolality?
ADH
Where is ADH stored
posterior pituitary gland
ADH mechanism of action
Bind to V2 receptors on CD
Stimulates production and binding of aquaporin2 on apical side, for water reabsorption
If plasma ADH concentration is low is there diuresis or anti-diuresis?
Diuresis (excessive urine production)
What regions are osmoreceptors found in the hypothalamus?
Subfornical Organ (SFO)
Organum Vasculosum of Lamina Terminalis (OVLT)
What are three causes of primary polydipsia?
Psychogenic (schizophrenia),
Brain Damage,
Organic Brain Disease (Dementia - Alzheimer’s)
What are five conditions that cause secondary polydipsia?
DIabetes Mellitus,
Nephrogenic Diabetes Insipidus (AVP resistance)
Conn’s Syndrome (1º hyperaldosteronism)
Chronic Kidney Failure,
Sickle Cell Anaemia
What are the four functions of angiotensin II?
Increased sympathetic activity
ADH release
Thirst
Aldosterone release
What are some common presentations of undiagnosed diabetes mellitus?
Polyuria, Unhealing wounds, erectile dysfunction, polydipsia
What is the side effect of Furosemide?
It is a loop diuretic used to treat congestive heart failure
side effect = polydipsia
What is the BMI for healthy weight?
18.5-24.9
