Disordered Defecation Flashcards
Defecation and Micturition Similarities
Storage (accommodation)
Outlet (internal and external sphincters)
Pelvic floor muscles (levator ahi muscle, puborectalis sling, innervated by pudendal nerve)
Innervation
Storage: Accommodation
Waste stored at low-pressure
Low pressure prevent reflux
Internal Sphincter
Involuntary muscle
Tonically contracted to prevent leakage
Automatically relaxes as filling occurs
External Sphincter
Striated muscle Consciously controlled Not maximally contracted Contracts more when "time not right" Overrides internal sphincter
Pelvic Floor Muscles
Supports pelvic organs
Levator ani muscle and puborectalis sling
Voluntary control
Wrap around urethra, vagina, rectum as pass through pelvic floor
Peripheral Nervous System: Sympathetic Innervation
Continence nerves T10-L2
- gut motility and secretion
Relaxes bladder
Tightens internal sphincter
Peripheral Nervous System: Parasympathetic Innervation
Continence nerves S2-S4
+ gut motility and secretion
Contracts bladder
Central Nervous System: Pons
Unconscious
Initiates bladder contractions
Instructs internal sphincter to relax
Central Nervous System: Frontal Lobe
“Social Continence”
Interrupts message from pons
If time is right, sphincter relaxes to allow urine/BM passage
Factors Contributing to Bowel Control Issues
Antibiotics Enteral feedings Hypoproteinamia Crohn's Chronic Ulcerative Colitis Bowel obstruction Fecal impaction Radiation therapy Chemotherapy
Mechanisms for Bowel Continence
Transit time Stool consistency Stool volume Awareness of filling Intact pelvic floor and sphincter muscles Rectal capacity and compliance
Intake/Output Volume
Oral fluid intake: 1-2 L/day
Small intestine secretions: 6-7 L/day
Volume at ileocecal valve: 1-1.5 L/day
Volume in rectum: 50-100 cc/day
Small intestine absorbs 7-9 L/day
Colon absorbs 1 L/day
Mucosal Layer
Secretes mucus to lubricate mucosal lining = forward movement of food bolus and prevention of abrasions
Villi
+ absorptive surface
Transit, Consistency, Volume Factors
Ileosecal valve Structures intact Absorption Peristalsis Segmentation and austral contractions Diet (fiber)
Ileocecal Valve
Gradual release of contents into colon
Prevents backward movement of stool
Segmentation
Mixing action
Haustral Contractions
Pushes stool forward
Myenteric plexus aka Auerbach’s plexus
Regulates colon motility
Detects bowel distention and luminal irritants
Between muscles in colon wall
Intrinsic (enteric) NS
Submucosal Innervation: Meissner’s plexus
Detects bowel distention and luminal irritants
Intrinsic (enteric) NS
Increased Rectal Capacity
2nd to chronic delayed defecation, - sensitivity to distention, ineffective contractility
Decreased Rectal Capacity/Compliance
Experience normal sensation and muscle function
Extreme urgency
Associate w/ damage to mucosal surface (IBD, radiated bowel)
Awareness of Rectal Filling
Normal volume delivered in normal period of time
En Masse contractions move stool forward (1 - 2x/day)
Voluntary
Conscious control in anal canal (transition zone)
Anal Canal
Columnar epithelium above Dentate Line
Squamous epithelium below Dentate Line
Begin to detect sensation in Transition Zone
Rectoanal Inhibitory Reflex
Rectum distends
Internal anal sphincter (IAS) relaxes automatically (reflexively)
Sampling Reflex
With internal sphincter relaxed, rectal contents come into contact w/ anal canal
Squamous epithelial cells discriminate btwn flatus and stool, liquid and solid
Anal Wink
Reflex
Indicates pudenal nerve intact
Stroke perianal skin
External sphincter contracts = contraction of muscle around anus
Forces Influencing Defecation
Propulsive: val salva, gravity, peristalsis
Resistive: External compression, rectal compliance, external sphincter, puborectalis muscle
Upper Urinary Tract
Kidney: 60 cc/hr urine production, + w/ age
Renal pelvis: store 15-30 cc urine
Ureter: peristalsis moves 5-15 cc urine to bladder
Lower Urinary Tract
Bladder: detrusor, body, neck, base
Detrusor compliance: stores 300-600 cc, - compliance = + filling pressure = urine reflux
Urothelium: Transitional epithelium
Urethra
Urethra
Collapsible
Proximal urethra is sphincter mechanism in males
Entire urethra functions as female sphincter
Distal 2/3 fused to vaginal wall
Coaptation: mucus +surface tension and adherence
Voluntary control of sphincter and pelvic floor
Innervated by Pudendal from S2-S4
Bladder Filling and Storage
Detrusor relaxed / Sphincter contracted
Controlled by Sympathetic Nervous System (T10-L2)
Bladder Emptying Phase
Controlled by Parasympathetic (S2-S4)
Detrusor extends
Signal sent to micturition center (S2-S4)
Pons replies to contract bladder (empty)
Frontal lobe interrupts Pons if time not right to void
If time right, sphincter relaxes
Age-Related Bladder Control
- bladder capacity \+ urine output at night - sensory awareness of filling - urinary flow rate - urethral closing pressure and length 2nd to - estrogen - ability to delay voiding
Bowel Diary
Frequency, volume, consistency of continent and incontinent stools
Keep 1-2 weeks
Physical exam
Tighten anus and bear down: note weakness, nerve damage, prolapse, sphincter disruption
Digital exam: tumor, impaction, prolapse, hemorrhoids, musculature exam
Anorectal Manometry
Measures pressures w/i anal canal during rest, contraction, relaxation
Localizes and quantifies sphincter deficits
Determines length of anal canal
Provides estimate of sampling reflex, rectal sensation/capacity/compliance
Mean and maximal resting pressure
Mean and maximal squeeze pressure
Mean and Maximal Resting Pressure
Reflects status of function of internal anal sphincter
Mean and Maximal Squeeze Pressure
Reflects status of function of external anal sphincter
Anal EMG
Useful when evaluating anal incontinence 2nd to disruption of external anal sphincter mechanism
Benefit in locating severed ends of sphincter muscle
PAINFUL
Pudendal Nerve Terminal Motor Latency (PNTML)
Checks for nerve damage to EAS (pudendal neuropathy)
+PNTML (2.2+ msec) = - conduction in terminal part of pudendal nerve to the EAS
Assesses - rectal filling sensation
May influence prognosis after surgical corrections of sphincter defects
Endoanal Ultrasonography (EAUS)
Probe size of finger inserted into anal canal
Probe rotates 360 to provide image of IAS and EAS
IDs defects, asymmetry, thickness of sphincter muscle
Simple, painless, accurate, repeatable
Follow-up after surgical correction of incontinence
- need for EMG 2nd to correlation w/ absent electromyographic activity
Rectal Compliance Study
Ability of rectum to distend or stretch and store stool at low pressure
Defecography
Evaluates function of anorectal unit during BM
IDs pelvic floor dysfunction affecting stool evacuation (prolapse, rectocele, non-relaxing puborectalis)
Barium Enema
View structures of colon
Motility Studies
Follow contrast material progression through intestinal tract
Bristol Stool Scale: Type 1
Stools in separate, hard lumps
Nut-like
Stool remains in colon longest amount of time
Sign of constipation
Bristol Stool Scale: Type 2
Sausage-like stool
Lumpy
Indicate toxic constipation and need for intestinal cleaning
Bristol Stool Scale: Type 3
Normal
Sausage-like
Cracks is surface
Bristol Stool Scale: Type 4
Normal
Smooth and soft
Form of sausage or snake
Bristol Stool Scale: Type 5
Soft blobs w/ clear-cut edges Easily pass through digestive system Soft diarrhea Possible risk of bowel disease Indicates toxic and need for regular intestinal cleaning