Diseases Of WBCs, Lymph Nodes, Spleen And Thymus Flashcards
Plasma cell noplasms are associated with
Increased monoclonal igs (called M component in myeloma)
Excess light chain levels
Seen in blood
Excreted in urine as bence jones proteins
Plasma cell neoplasms are also called
Monoclonal gammopathies
Paraproteinemia
Waldenstorm macrogobulinemia
Increased igM levels
⬇️
Increased viscosity of blood
Heavy chain disease
ASSOCIATED WITH
- Lymphoplasmocytic lymphoma
- Small bowel marginal zone lymphoma (mediterranean lymphoma)
FEATURE
Increased synthesis ans secretion of heavy chains
Primary of immunocyte associated amyloidosis
Monoclinal proliferation of plasma cells that secrete light chains and deposit as amyloid
Multiple myeloma is associated with
Lytic bone lesions
Hypercalcemia
Renal failure
Acquired immune abnormalities
Multiple myeloma age grouo
65 to 70