Diseases of the Stomach Pt. 2 Flashcards
Medical therapy in egus 2 goals:
-Control gastric acid
– Mucosal protectant
Diet modifications include increasing periods of fasting and decreasing roughage, reduce grain/concentratesT/F
F limiting fasting dapat at increasing roughage
roughage to be given in modifications include
- pasture turnout (green grass)
- free choice hay
- Alfalfa hay-dietary antacid
- Calcium Carbonate supplements
______ may help buffer stomach contents by providing it throughout day and night
Alfalfa hay/mixed alfalfa hay
Concentrates should be fed in small amounts, distributed in at least 5 feedings
throughout day (base on requirements?)
and should not exceed 0.2 kg of grain/100kg BW T/F
F - 3 feedings dapat , 0.5kg
Contains protective factors
(phospholipids) for stomach lining
* Rancidity can be a problem
– Produces ketoaldehydes which are
ulcerogenic
* Steam pasteurization can help
decrease potential for rancidity
– Storage in refrigerator
Rice bran / oil
Decreases stomach acid
* Increases
protective factors (PG)
* Provides Omega
3 & 6 fatty acids
* Dose: 8 oz once to
twice daily
Corn oil
Management Modifications
Limit stressful events
* Long-term stall
confinement
* Trailering
* Overcrowding
* Semen collection and
natural breeding?
Neutralizing agents and example of answer
antacids
- neutralize HCl
Al/Mg hydroxide
Antisecretory agents
Histamine H2 receptor
antagonists (Zantac™)
– Acid pump inhibitors
(GastroGard™)
Allows
Healing/Improvement of Ulcers
omeprazole
example of Histamine H2 Receptor Antagonists
Role: Competitive inhibition of the
interaction of histamine of w/ _____
inhibition of gastric acid secretion is dose dependent T/F
Zantac® (ranitidine), Tagamet®
(cimetidine)
parietal cell
T
zantac is cheap (generic), known for its availability, and must be administered 2x daily T/F
F - 3x dapat
adheres to ulcerated mucosa; stimulates mucus secretion and enhances PGE synthesis
Sucralfate (sucrose and AlOH3)
– best for glandular mucosal lesions and duodenum
Sucralfate (sucrose and AlOH3)
H. pylori has been associated with the stomach of horses, resulting in EGUS T/F
F - not associated in EGUS
Antimicrobials are not used in horses with resistant EGUS (TMS, Metronidazole,
Bismuth compounds) T/F
F - used dapat
Duodenal Ulcers/Stricture is a part of EGUS commonly seen in adult horses T/F
Associated with __, ___, and diarrhea, delayed gastric emptying
Associated with __ ulcers
F - foals
bruxism, ptyalism
esophageal
duodenal ulcers/strictures can be diagnosed via
clinical signs, __, __, ___,
duodenoscopy, radiology, necropsy
radiology: gastric emptying with barium swallows (liquid meal=30 minutes)
treatment of DU/S
omeprazole (4mg/kg, IV Q24h, 28 days)
ome (0.5mg/kg PO, Q24h)
Ranitidine (6.6 mg/kg, PO, Q8h) T/F
Surgery: _
F - 4mgkg yung PO, O.5 yung IV
Gastrojejunostomy
Gastric neoplasia is uncommon in older horses, with adenosarcoma as the MOST common type. T/F
F - SCC ang pinakacommon
others lng ang adeno at lymphosarcoma
the gastric neoplasia Arises from squamous mucosa and
metastasizes to the abdominal cavity and
viscera and/or extends up the trachea T/F
T
Magnets - pass the magnet into the jejunum then another magnet stays in the stomach → join together -> block blood supply in the area -> anastomosis
What is this technique called?
natural orifice transluminal endoscopic surgery (NOTES)
Clinical signs: of gastric neoplasia
– Chronic weight loss
– Anemia
– Naso-gastric reflux
– Colic
gastric neoplasia and EGUS can both be diagnosed by necropsy T/F
gastric neoplasia, gastric impaction and EGUS can both be diagnosed by endoscopy and is definitive t/f
F - duodenal ulcers/strictures instead of EGUS
T - not sure lang sa impaction kung definitive
treatment of gastric neoplasia includes vincristine and surgery T/F
prognosis of GS is usually good T/F
F - no tx
F - grave
gastric impaction is a frequent cause of colic in horses and is due to dry feed materials and decreased water intake T/F
this occurs frequently on spring where dry hay is fed and water intake is lower T/F
F - infrequent
F - winter
Diagnosed at surgery in horses with colic and is treated with dioctyl sodium succinate (DSS, 5% soln via NG tube in ___ fluid) T/F
During lavage at surgery, it can resolve in 24-36 hours T/F
T - 4-6L
F - 24-48
gastric impaction can be treated with exlopratory laparotomy T/F
T
