Diseases of the salivary glands and neck masses Flashcards
salivary gland stones aka sialolithiasis
-salivary gland stones usually occur in major salivary glands (parotid, submandibular, and sublingual)
-anatomy of glands and ducts affects where stones are likely to lodge and also affects the choice of therapies
-parotid glands and stensen’s duct
-submandibular glands and whartons duct
-sublingual glands- either empty into whartons duct or directly into the floor of the mouth
-minor salivary glands drain directly into mouth
sialolithiasis
-pathogenesis of stone formation is not known, but relative stagnation of salivary flow and salivary calcium concentration are thought to be important
-compositions largely of calcium phosphate and hydroxyapatite with smaller amounts of magnesium, potassium, and ammonium
-inflammation of the salivary gland or duct and localized injury often contribute
-submandibular gland may be more prone to stone formation because the duct is long, the flow of saliva is slow and against gravity, and the saliva is more alkaline with high mucin and calcium constant
-80-90% of all stones
sialolithiasis risk factors
-dehydration
-diuretics
-anticholinergic medications
-trauma
-gout
-smoking
-hx of nephrolithiasis
-chronic periodontal disease
signs and symptoms sialolithiasis
-typically presents with pain and swelling in the involved gland
-aggravated by eating or by anticipation of eating
-can also present as painless swelling or may be noted incidentally on physical examination or on radiographs
sialolithiasis diagnosis
-based on characteristic hx and physical exam
-sudden onset of swelling and pain in the affected gland associated with eating or anticipation of eating
-stone may be seen at the opening of the affected salivary gland duct or palpated along the course of the duct
sialolithiasis imaging
-provides location of stone, helpful to identify complications (abscess)
-solid lesions- concerning for malignancy
-cystic lesions- typically benign
-CT- w/o contrast is imaging modality of choice
sialolithiasis treatment
-conservative management
-stay hydrated
-apply moist heat to area
-massage gland
-milk duct
-supportive care- discontinue medications with anticholinergic effects that reduce salivary flow (diphenhydramine and amitriptyline)
-NSAIDs PRN
-complications- acute bacterial sialadenitis and abscess formation
neck mass causes
-very common clinical finding
-1. congenital
-2. inflammatory/infectious
-3. neoplastic
-4. traumatic- anastamoses
-5. metabolic- thyroid
acute bacterial sialadenitis
-AKA suppurative sialadenitis
-can occur in the absece of stone: older adults or post op pts
-parotid gland most commonly involved
-staph aureus- MC pathogen
-S&S-
-increased pain and swelling with meals
-tenderness and erythema of duct opening
-pus +
indications for referral for acute bacterial sialadenitis
suspected salivary gland tumor
-failure to improve with conservative management
-recurrent symptoms
-specialist management- sialoendoscopy
viral sialadenitis
-aka viral parotitis
-MCC is mumps virus
-acute pain and swelling of one or both parotid glands
-frequently accompanied by nonspecific prodrome
-low grade fever, malaise, headache, myalgias, and anorexia
-these symptoms are generally followed within 48 hours by development of parotitis
-less common viral etiologies include coxsackie viruses A and B, echovirus, parainfluenza virus, influenza A, and epstein-barr virus
-self limiting supportive care
HIV parotitis
-non painful swelling of gland occurs
-otherwise pt is asymptomatic
parotitis in tuberculosis
-chronic nontender swelling of one parotid gland occurs, or a lump is noted within the gland
-symptoms of tuberculosis are found in some cases
Sjogren syndrome
-recurrent or chronic swelling of one or both parotid glands with no apparent cause is noted
-it is frequently associated with autoimmune disease
-discomfort is modest in most cases and is related to dry mouth and eyes
salivary gland tumors
-uncommon
-rare, accounting for 6-8% of head and neck tumors
-parotid gland is most frequent site of salivary gland tumors (80%-85% of SG tumors)
-75% benign and 25% malignant
-most common type of benign salivary gland tumor is pleomorphic adenoma
-most common malignant salivary gland tumors are mucoepidermoid carcinoma and adenoid cystic carcinoma
-salivary gland cancers vary in their aggressiveness and their propensity to recur and metastasize
facial nerve
-facial nerve goes through parotid gland
-parotid gland malignancy will weaken the facial nerve
thyroglossoduct cyst
-use dye to identify
-thyroid can go through base of tongue as a developmental variation
-can be easily infected in this variation
-midline
salivary gland tumors
-radiation exposure
-smoking (Warthin tumor)
-viral infection?
-epstein barr virus (EBV)
-HIV
-HPV
-environmental factors and industrial exposure to factors such as rubber manufacturing, hair dressers, beauty shops, and nickel compounds
salivary gland tumors presentation
-typically a painless mass or swelling of parotid, submandibular, or sublingual gland
-parotid mass (+) signs or symptoms indicative of facial nerve involvement (facial nerve paralysis)
-malignant -> benign tumor
-diagnosis:
- CT vs MRI of salivary gland tumor for better assessment
-FNA bx or US core bx for tissue collection -> definitive dx
central neck
-hyoid bone
-thyroid and cricoid cartilages
-thyroid isthmus
-trachea
lateral neck
-divided by the sternocleidomastoid muscle (SCM) into an anterior triangle
anterior triangle of neck
-superiorly- inferior border of mandible (jawbone)
-laterally- anterior border of sternocleidomastoid
-medially- sagittal line down the midline of the neck
posterior triangle of the neck
-anterior- posterior border of the SCM
-posterior- anterior border of the trapezius muscle
-inferior- middle 1/3 of clavicle
lymph nodes
-1. Preauricular—in front of the ear
-2. Posterior auricular—superficial to the mastoid process
-3. Occipital—at the base of the skull posteriorly
-4. Tonsillar—at the angle of the mandible
-5. Submandibular—midway between the angle and the tip of the mandible.
-6. Submental—in the midline a few centimeters behind the tip of the mandible
-7. Superficial cervical—superficial to the sternomastoid
-8. Posterior cervical—along the anterior edge of the trapezius
-9. Deep cervical chain—deep to the sternomastoid and often inaccessible to examination.
-10. Supraclavicular—deep in the angle formed by the clavicle and the sternomastoid
cervical lymph node evaluation
-size- normal < 1 cm; abnormal > 1.5 cm**
-mobility- normal movable; abnormal decreased/fixed
-consistency- normal soft, fleshy; abnormal firm/rubbery/matted
-PRESENCE OF MASS:
-parotid gland not normally present -> abnormally present
-thyroid gland not normally present -> abnormally present
normal neck structures that may be palpable
-transverse process of C1 vertebra
-hyoid bonne
-thyroid and cricoid cartilage
-atherosclerotic carotid bulb
neck mass: very common clinical finding
-1. congenital
-2. inflammatory/infectious
-3. neoplastic
-4. traumatic
-5. metabolic
congenital anomaly neck mass
-CT (contrast medium optional)
-excisional bx
-ENT referral
-differentials- thyroglossal duct cyst, branchial cleft cyst, lymphangioma, hemangioma