diseases of muscles and nerves

Question 1

what must have occurred if we wee clusters of type 1and clusters of type 2 nerve fibers

Answer 1

denervation atrophy+ reinnervation

Question 2

target and angular fibers indicate

Answer 2

denervation atrophy

Question 3

angular atrophy + prolonged immobilization. what kind of atrophy

Answer 3

diffuse

Question 4

profound loss of muscle function, weakness

Answer 4

muscular dystrophy

Question 5

dystrophy vs atrophy

Answer 5

dystrophy is an irreversible destructive process

atrophy is an adaptation

Question 6

affects males
progessive weakness of proximal muscles
calf muscles display compensitory hypertrophy

Answer 6

duchenne muscular dystrophy

Question 7

frameshift mutation of dystrophin gene=

Answer 7

duchenne msuclualr dystrophy

Question 8

dystipohin gene shows segmental deletion in

Answer 8

becker muscular dystrophy

Question 9

histologiclly see fibrofatty cahnges, necrosis of individual fibers, random variation in msucle size

Answer 9

duchenne md

Question 10

increased number of CTG repeats
anticipation
inability to relax muscle= loss

Answer 10

myotonic dystrophy

Question 11

floppy infant

Answer 11

congenital myopathy

Question 12

floppy at birth.

loss of mitochondria from center of type 1 cells= large clearing

Answer 12

central core disease

Question 13

tangles of small rod shaped granules

Answer 13

nemaline myopathy

Question 14

ragged red fibers

Answer 14

mitochondrial myopathy

Question 15

muscle weakness worsening with stress use illness

autoantibodies against ach receptor

Answer 15

myasthnia gravis