Diseases of Esophagus Flashcards

1
Q

sensation of impaired passage of food or liquids from mouth the stomach

A

DYSPHAGIA

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2
Q
  • painful swallowing
  • Ranges from a dull ache to stabbing pain
  • Usually represents a severe inflammatory process.
  • Rarely associated with severe GERD or malignancy
A

ODYNOPHAGIA

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3
Q
  • substernal discomfort

- Can mimic cardiac disease (e.g., can radiate to the arm or jaw) (need to rule it out)

A

CHEST PAIN

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4
Q
  • Difficulty transferring food from the mouth to the upper esophageal sphincter
  • Neurological disorders
    CVAs (brainstem), Parkinson’s, Motility
  • Anatomic
    Neoplasms, Zenker’s diverticulum
A

OROPHARYNGEAL DYSPHAGIA

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5
Q

Difficulty with the passage of ingested material from the hypopharynx to the stomach

Neuromuscular
- Diffuse esophageal spasm, Achalasia, Scleroderma

Obstructive lesions
- Strictures, rings, foreign body, carcinoma

A

ESOPHAGEAL DYSPHAGIA

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6
Q
  • outpouching in oropharyngeal/upper GI region
  • main symptom: Dysphagia
  • ~85% occur in individuals >50 years old
  • Diverticulum can be large enough retain food which can result in fullness or gurgling in the neck, coughing or aspiration, regurgitation of retained food, obstructive symptoms by compression
  • requires surgical intervention
A

ZENKER’S DIVERTICULA

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7
Q
  • Failure of relaxation of lower esophageal sphincter due to loss of myenteric/Auerbach’s plexus
  • main symptom: Dysphagia
  • distal esophageal sphincter is closed; above the sphincter, the esophagus is dilated b/c can’t push food past the sphincter –> “Bird’s Beak esophagus”
  • Insidious, with progressive dysphagia to solids first, then liquids
  • TRIAD OF FINDINGS: Increased LES resting pressure; Inability of the LES to relax; Absence of peristalsis in body of the esophagus
A

Achalasia

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8
Q
  • fibrous tissue that is inside the esophagus that disrupts things coming through (dysphagia)
  • “steakhouse syndrome”: Not an emergency, b/c you think you can pass it
  • If you have stuff staying in the esophagus for too long, you can eventually tear it
A

Schatzki’s ring

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9
Q
  • Most commonly Candida (white pseudomembrane); can also be herpes (punched-out ulcers) or CMV (linear ulcers)
  • person had infection of lining of the esophagus, causing pain (odynophagia)
  • Affects HIV patients, steroids, chemotherapy, diabetes
A

Esophagitis

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10
Q
  • mucosal injury commonly due to: doxycycline, iron, potassium, vitamin C, quinidine, aspirin, NSAIDs, alendronate
  • Main symptom: Odynophagia
  • looks like huge ulcer with clot
  • resolves when cease taking medication
A

MEDICATION-INDUCED ESOPHAGITIS

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11
Q
  • appears as “corkscrew” esophagus; sequeezing, w/o normal peristalsis
  • Primary symptom: chest pain
  • due to: Acid reflux into esophagus, which irritates the lining and causes spasm & pain, or may be due to heart condition
A

Diffuse esophageal spasm

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12
Q
  • Constellation of symptoms and/or the presence of esophageal tissue damage due to the reflux of gastric contents into the esophagus
  • primary offensive factor is acid
  • Common abnormalities: LES incompetence, Anatomic disruption of relationship between LES and diaphragm (sliding hiatal hernia), or Increased intraabdominal pressure (obesity, pregnancy)
  • TYPICAL SYMPTOMS: Substernal discomfort, burning irritation (“heartburn”); Regurgitation
  • ATYPICAL AND EXTRAESOHPAGEAL SYMPTOMS: Dysphagia (from inflammation or scarring), Non-cardiac chest pain; Throat discomfort, hoarseness; Coughing, wheezing, bronchospasm; Gingivitis, poor dentition
  • Poor correlation between heartburn severity and degree of esophagitis
A

Gastroesophageal Reflux Disease

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13
Q
  • Primary role is to determine evidence of tissue injury and/or the presence of Barrett’s epithelium
  • Used when there is dysphagia or evidence of bleeding
A

Endoscopy

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14
Q
  • useful when there is doubt about symptom etiology; atypical symptoms
  • monitoring medication effects
  • pre-operative evaluation
A

pH monitoring

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15
Q
  • Useful to assess presence of a motility disorder

- Performed as a pre-operative assessment

A

ESOPHAGEAL MANOMETRY

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16
Q
  • lining is disrupted, but than heals improperly, causing narrowing of lumen
  • results in dysphagia
A

Strictures

17
Q
  • Columnar epithelium (salmon-colored) resulting from metaplasia following acid-related epithelial injury (normally is squamous epithelium); gastric cardiac and fundus are normally columnar
  • pre-malignant; can progress to adenocarcinoma (40x greater risk than general population)
A

Barrett’s epithelium

18
Q
  • Diagnose with EGD with biopsies
  • Squamous cell carcinoma: linked to Tobacco and alcohol
  • adenocarcinoma: linked to Barrett’s epithelium
  • Only curative treatment is surgery
A

Esophageal Carcinoma