Diseases of Bone Flashcards
What is Ehlers-Danlos
it affects type three collagen in the advantitia of the blood vessels and predisposes these blood vessels to saccular anuerisms
What determines how much weight the bone can bear?
the mass of the bone
What is osteopaenia?
a lower bone mass
What is osteoporosis?
a more severe form of osteopaenia
How much bone mass do you lose between the ages of 25-about 50?
0.3-0.5%
What happens when women hit menopause?
women begin to lose bone mass by about 1.5-3% per year
What causes women to lose so much bone mass during menopause?
Drop in estrogen levels
How much bone mass have older women lost?
35-50%
How much bone mass have older men lost?
20-35%
What type of bone generally breaks if someone has osteopaenia?
cancellous
how many people are diagnosed with osteoporosis
10-12 million people
How many women are diagnosed with osteoporosis?
8 million women
how many millions of people have undetected osteoporosis?
30 million people
how many fractures does osteopososis cause per year?
1.5
What is the most common fracture with osteoporosis
vertebral
What it is called when patients are hunched over?
kyphosis
how many vertebral fractures occur per year?
700,000
How many hip fractures occur per year?
300,000
what is it called when people turn their wrists out when they fall
Colle’s fracture
What is it called when people turn their wrists in when something happens?
Smith’s fracture
What is the largest risk factors for getting osteoporosis?
gender
What races are most susceptible to osteoporosis
white, southeast Asian
What is osteogenesis imperfects
when arginine is substituted for arginine and the triple helix spacing between these is larger
