Diseases of Bone Flashcards

1
Q

What is Ehlers-Danlos

A

it affects type three collagen in the advantitia of the blood vessels and predisposes these blood vessels to saccular anuerisms

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2
Q

What determines how much weight the bone can bear?

A

the mass of the bone

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3
Q

What is osteopaenia?

A

a lower bone mass

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4
Q

What is osteoporosis?

A

a more severe form of osteopaenia

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5
Q

How much bone mass do you lose between the ages of 25-about 50?

A

0.3-0.5%

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6
Q

What happens when women hit menopause?

A

women begin to lose bone mass by about 1.5-3% per year

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7
Q

What causes women to lose so much bone mass during menopause?

A

Drop in estrogen levels

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8
Q

How much bone mass have older women lost?

A

35-50%

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9
Q

How much bone mass have older men lost?

A

20-35%

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10
Q

What type of bone generally breaks if someone has osteopaenia?

A

cancellous

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11
Q

how many people are diagnosed with osteoporosis

A

10-12 million people

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12
Q

How many women are diagnosed with osteoporosis?

A

8 million women

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13
Q

how many millions of people have undetected osteoporosis?

A

30 million people

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14
Q

how many fractures does osteopososis cause per year?

A

1.5

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15
Q

What is the most common fracture with osteoporosis

A

vertebral

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16
Q

What it is called when patients are hunched over?

A

kyphosis

17
Q

how many vertebral fractures occur per year?

A

700,000

18
Q

How many hip fractures occur per year?

A

300,000

19
Q

what is it called when people turn their wrists out when they fall

A

Colle’s fracture

20
Q

What is it called when people turn their wrists in when something happens?

A

Smith’s fracture

21
Q

What is the largest risk factors for getting osteoporosis?

A

gender

22
Q

What races are most susceptible to osteoporosis

A

white, southeast Asian

23
Q

What is osteogenesis imperfects

A

when arginine is substituted for arginine and the triple helix spacing between these is larger