Diseases Flashcards
Cushing’s Syndrome
Hyperadrenalism
Increased [cortisol] supresses ADH
↑ Na ↓ K
Pituitary tumors
Addison’s Disease
Hypoadrenalism
1° ; involving entire adrenal cortex
↑ ACTH ↓ Cortisol ↓ Aldosterone
↑ K ↓ Na
Hypoglycemia
Conn’s Syndrome
Hyperadrenalism
1° hyperaldosteronism
Increase secretion of aldosterone
↑ Na ↓ K
Adrenal adenoma
SIADH
Syndrome of Inappropriate Antidiuretic Hormone
Overproduction of ADH from an ectopic site
↓ Na ↓ Plasma Osm ↑ Urine Osm
Lung cancer
Fanconi’s Syndrome
Renal tubular defects
*returns nutirents to blood, remaining fluid turns to urine
↓ PO4 (hypophosphatmia)
Rickets & Osteomalacia
Metabolic bone disorder
*imbalance between bone formation and resorption
Defective mineralization of bone due to Vit D Def or Phos Depletion
↓ PO4
Secondary Hyperaldosteronism
Hyperadrenalism
2° caused by decrased blood flow to kidney
↓ K ↑ Na
CHF, Nephrotic Syndrome, Stenosis
Rhabdomyolysis
Breakdown of sk. muscle after trauma
*myoglobinuria
↑ K (hyperkalemia)