Disease management Flashcards
What is the treatment of ACS?
-Morphine
-Oxygen 15L
-Nitrates
-Aspirin 300mg
-Ticagrolol 180mg then 90mg
NSTEMI: PCI in 14days PLUS Echo
STEMI: PCI within 2hours
What is the treatment of an aortic dissection?
Unstable: 0.5-1micro NorA/Dobutamine & resus
Acute: 1-5mg IV Labetalol, Morphine, Vasodilators, surgery
Ongoing: Metoprolol
What is the treatment of PE?
High Suspicion: 15L high flow O2 & ventilation 500ml fluids 15mg Rivaroxaban/ 1mg Enoxaparin CTPA: Alteplase 0.5-1micro IV NorA/Dobutamine
Acute confirmed PE: 15L high flow & ventilation 500ml fluids 100mg IV Alteplase over 2hours 15mg Rivaroxaban 0.5-1micro IV NorA/Dobutamine
Failed Thrombolysis:
Above
IVC filter placement&Surgery
Fondaparinux/LMWH for 5days till INR>2 for 24hours
First Unprovoked no RF: 3months anticoagulation
First Unprovoked w/RF: 3months anticoagulation then review
What is the treatment of DVT?
Proximal & distal DVT of the leg: 15mg Rivaroxaban Physical Activity Gradient stockings Pregnancy: LMWH (Enoxaparin/Heparin) Active bleeding: IVC filter
What is the treatment of tension pneumothorax?
Thoracocentesis- 14G catheter into 2nd intercostal space, mid-clavicular
Chest drain- Safety triangle, 5th intercostal space, mid-axillary
15L/min high flow oxygen
What is the treatment of acute exacerbation of COPD?
Short acting bronchodilator: 2.5-5mg Salbutamol, 0.25-0.5mg ipratropium
Systemic Corticosteroids: 30-60mg Prednisolone
Inhaled corticosteroids (50-100micro Beclometasone)
Assist ventilation: NIV, mechanical/invasive ventilation
Oxygen
Antibiotics: 100mg Doxycycline/250mg Tetracycline
Consider: MI, PEN, CCF
What is the treatment of CAP?
CURB 0-1= Amoxicillin (allergy: Doxycycline)
CURB 2= Amoxicillin & Clarithromycin (allergy: Doxycycline/Levofloxacin)
CURB >3= IV Co-Amox & IV Clarithromycin (allergy: Cefuroxime & Clarithromycin)
What is the treatment for HAP?
Early: Doxycycline/ Co-Amox (allergy: Doxycycline/Levofloxacin)
Late: Co-Trimoxazole/ Amoxicillin & Temocillin (allergy: Linezolid & Ciprofloxacin)
What is the treatment for pseudomonas pneumonia?
IV Piperacillin/Tazobactam
Allergy: Linezolid & Ciprofloxacin
What is the treatment for pre-renal AKI?
Fluids: Crystalloid (Saline)
Vasopressor: 1 micro Dopamine/Epinephrine, NorE
Vol Overload: 20-40mg Furosemide
Renal replacement
What is the treatment for intrinsic AKI?
Treat underlying condition
Crystalloid
Vol Overload: 20-40mg Furosemide
Renal replacement therapy
What is the treatment for post-renal AKI?
Catheterization
Relieve obstruction: Stenting, lithotripsy, nephrostomy
Diuretic: 20-40mg Furosemide
Renal replacement therapy
What is the treatment for DKA?
Acute:
1-1.5L Fluids (Isotonic saline)
5% Dextrose w/0.5% NaCl when glucose= 11.1
IV insulin
IV 20-30mEq/L potassium phosphate w/fluids
5-10micro Dopamine
Mild: Isotonic Saline for 1hour then add potassium phosphate if K<3.3
What is the treatment for hyponatraemia?
Acute: 100-300mL Hypertonic 3% saline infusion
Supportive
Chronic/Asymptomatic: Isotonic 0.9% saline, Spironolactone
hypovolaemic: 250-1000ml 0.9% normal saline
What is the treatment for hyperkalaemia?
Significant: IV 10% CaCl/ 10% Ca gluconate
Nebulised Salbutamol 5mg
IV Insulin Dextrose 10u in 50mls w/50% dextrose
IV sodium bicarb
IV Furosemide
Severe: Haemodialysis
Emergency: Cardioversion
What is the treatment for cellulitis?
Severe: IV Vancomycin
Acute: Extremity= Fluclox, Orbital= Vancomycin & Ceftriaxone, Diabetic foot= amoxicillin & Doxycycline
Animal bite: Amoxicillin/ Trimethoprim
What is the treatment for sepsis?
Oxygen
Respiratory: Cefotaxime/ Co-Amox/Moxifloxacin
MRSA cover: Vancomycin
Pseudomonas: Ciprofloxacin
IV Crystalloids
Adjunct: NorA, IV hydrocortisone, Dobutamine
What is the treatment for cardiac arrest?
CPR & defibrillation
Adrenaline/Epinephrine 1mg every 3-5mins
Adjunct: Amiodarone, Magnesium (TdP)
What is the treatment for anaphylaxis?
Oxygen
IM epinephrine every 5-15mins
IV saline 1-2L
What is the treatment for a TIA?
Control underlying
Antiplatelet: Aspirin/Clopidogrel/Ticagrelol
Lipid agent: Statin
Stent/ carotid endarterectomy
What is the treatment for a subarachnoid haemorrhage?
Admit to ICU CP support: Ventilation, intubation Surgical clipping, endovascular coil embolization Nimodipine (Ca channel blocker) Senna/Docusate (Stool softner) Oxycodone/Fentanyl/Morphine Nitropresside (vasodilator)
What is the treatment for a generalised/Grand mal seizure?
IV/rectal Diazepam/Midazolam/Lorazepam
Sodium Valproate
What is the treatment for focal seizures?
IV/rectal Diazepam/Lorazepam
Carbamezepine
What is the treatment for paracetamol overdose?
IV Acetylcysteine
Ondansetron
Liver transplant (unknown time or within 8-24hours)
What is the treatment for alcohol withdrawal?
Acute: Diazepam/Lorazepam Phenobarbital Thiamine Folic acid Magnesium Sulfate Severe: Above Dexmedetomidine (sedative) Propofol
What is the treatment for a spontaneous pneumothorax?
Small: 15L/min high flow oxygen
Large: 15L/min high flow oxygen, chest tube thoracostomy, suction, video assisted thoracoscopy w/stapling of air leak & pleurodesis
How is an arrested patient managed?
ABCDE
3 attempts Synchronised DC shock w/chest compressions
300mg IV Amiodarone 10-20mins AND 1mg Adrenaline IV
Adrenaline repeated every 3-5mins (alternate shocks)
Consider 150mg IV Amiodarone after 5 shocks
How are broad QRS complexes treated?
Irregular: Seek specialist help
Regular: (VT) 300mg IV Amiodarone 20-60mins then 900mg over 24hours
(SVT w/BBB) treat as regular narrow tachycardia
How are narrow QRS complexes treated?
Regular: vagal manoeuvers
IV Adensoine 6mg bolus no effect then 12mg
Monitor via ECG
sinus rhythm achieved= consider anti-arrhythmic prophylaxis
No sinus rhythm= seek expert help & beta blocker
Irregular: Rate control- Diltiazem/beta blocker
HF- Amiodarone/Digoxin, assess VTE risk & anticoagulation
What is the treatment given to someone for life post-MI?
ACE inhibitor
Beta blocker
Statin
Dual anti-platetlet agents (Aspirin, Ticagrolol)
In a PE, what are the indications for thrombolysis?
Saddle thrombi
Haemodynamically unstable
Why is a beta blocker and an ACEi given after an MI?
Prevent heart failure
Turns dead tissue into scar tissue