Disease/Important associations Flashcards
Actinic (solar) keratosis
Precursor to suamous cell carcinoma
Acute gastric ulcer associated with CNS injury
Cushing ulcer ( increase intracranial pressure stimulates vagal gastric secretion
Acute gastric ulcer associated with severe burns
Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
Alternating areas of transmural inflammation and normal colon
Skip lesions ( Chrohn disease)
Aneurysm, dissecting
Hypertension
Aortic aneurysm, abdominal and descending aorta
Atherosclerosis
Aortic aneurysm, arch
tertiary syphilis (syphilitic aortitis) vasa vasorum destruction
Aortic aneurysm, ascending
Marfan syndrome ( idiopathic cystic medial degeneration)
Atrophy of the mammillary bodies
Wernicke encephalopathy (thiamine deficiency causing ataxia, opthalmoplegia and confusion_
Autosplenectomy (fibrosis and shrinkage)
Sickle cell anemia (hemoglobin S)
Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer
H. Pylori
Bacterial meningitis (adults and elderly)
Streptococcus pneumoniae
Bacterial meningitis ( newborns and kids)
Group B streptococcus/E.Coli (newborns), S.pneumoniae? Neisseria meningitidis (kids)
Benign Melanocytic nevus
Spitz nevus ( most common in 1st two decades)
Bleeding disorder with DpIb deficiency
Bernard-Soulier syndrome ( defect in platelet adhesion to von willebrand factor)
Brain tumor (adults)
Supratentorial: metastasis greater than astrocytoma ( including glioblastoma multiforme) greater than meningioma greater than schwannoma
Brain tumor (kids)
Infratentorial: medulloblastoma (cerebellum) or supratentorial : crainiopharyngioma
Breast cancer
Infiltrating ductal carcinoma
Breast mass
Fibrocystic change, carcinoma ( in postmenopausal women)
Breast tumor (benign)
Fibroadenoma
Cardiac 1 tumor (kids)
Rhabdomyoma, often seen in tuberous sclerosis
Cardiac manifestation of lupus
Libman-Sacks endocarditis ( nonbacterial, affecting both sides of mitral valve)
Cardiac tumor (adults)
Metastasis, primary myxoma ( 4:1 left to right atrium; “ball and valve”)
Cerebellar tonsillar herniation
Chiari II malformation
Chronic arrhythmia
Atrial fibrillation ( associated with high risk of emboli)
Chronic atrophic gastritis (autoimmune)
Predisposition to gastric carcinoma (can also cause pernicious anemia)
Clear cell adenocarcinoma of the vagina
DES exposure in utero
Compression fracture
Osteoporosis ( type I: postmenopausal women; type II: elderly man or woman)
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
Congenital cardiac anomaly
VSD
Congenital conjuagted hyperbilirubinemia (black liver)
Dubin-Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)
Constrictive pericarditis
TB (developing world) ; SLE (developed world)
Coronary artery involved in thrombosis
LAD greater than RCA greater than LCA
Cretinism
Iodine deficit/hypothyroidsim
Cushing syndrome
- Iatrogenic Cushing (from corticosteroid therapy)
- Adrenocortical adenoma (secretes excess cortisol)
- ACTH-secreting pituitary adenoma
- Paraneoplastic Cushing (due to ACTH secretion by tumors)
Cyanosis ( early; less common)
Tetralogy of Fallot, transposition of great vessels, truncus arteriosus
Cyanosis ( late; more common)
VSD, ASD, PDA
Death in CML
Blast crisis
Death in SLE
Lupus nephropathy
Dementia
Alzheimer disease, multiple infarcts
Demyelinating disease in young women
Multiple sclerosis
DIC
severe sepsis, obstetric complications, cancer, burns, trauma, major surgery
Dietary deficit
Iron
Diverticulum in pharynx
Zenker diverticulum ( diagnosed by barium swallow)
Ejection click
Aortic/pulmonic stenosis
Esophageal cancer
squamous cell carcinoma (worldwide); adenocarcinoma (U.S)
Food poisoning (exotoxin mediated)
S. aureus, B. cereus
Glomerulonephritis (adults)
Berger disease (IgA nephropathy)
Gynecologic maliganancy
Endometrial carcinoma ( most common in U.S); cervical carcinoma ( most common worldwide)
Heart murmur, congenital
Mitral valve prolapse
Heart valve in bacterial endocarditis
Mitral greater than aortic ( rheumatic fever, tricuspid ( IV drug abuse)
Helminth infection ( U.S.)
Enterobius vermiculars, Ascaris lumbrioides
Hematoma-epidural
Rupture of middle meningeal artery ( trauma; lentiform shaped)