Disease Clinical Signs Flashcards
Motor neurone disease
Fasciculation
Wasting spasticity
Entensor Plantar reflexes
Upper motor neurone signs
Guillain Barre syndrome
Areflexia
Sensory loss
Muscle wasting
Myaesthenia Gravis
Ptosis
Opthalmoplegia
Fatiguability
Slurred speech
What can cause areflexia?
Guillain Barre syndrome
Multiple sclerosis
Motor neurone disease
Hypothyroidism
What can cause collapse?
Syncope Epileptic fit Cardiac arrythmia Hypoglycaemia Pseudoseizure
Parkinson’s
Tremor; at rest, pill rolling Blank facial expression Less hand gesturing Less blinking less arm swing
Appendicitis
Guarding on examination Mass in right iliac fossa fever tenderness Rovsing's sign
Acute pancreatitis
Cullen sign Grey turner sign fever epigastric tenderness variable guarding
Common causes of LMN signs
Peripheral neuropathies
Radiculopathies
Anterior horn cell damage e.g. poliomyelitis or MND
Common causes of UMN signs
stroke, spinal cord pathology, MS, brain tumour
Causes of polyneuropathy
HIV Leprosy Guillain Barre Diabetes mellitus Renal failure
Which cranial nerves decussate?
optic
trochlear
facial
hypoglossal
Addison’s disease
weight loss
abnormal pigmentation; vitiligo etc
buccal pigmentation
Cushing’s syndrome
central obesity, round face hyperpigmentation bruising striae proximal muscle weakness oedema
Hypopituitarism
absent axillary hair
fine pale skin
testicular atrophy