Disease Flashcards
Due to the defect in intramembranous ossification
Cleidocranial dysostosis
1) aplasia of clavicle
2) increased transverse dia of skull
3) retarded ossif of fontanelles
Genetic as well as environmental
Endochondral ossif defect
Cause dwarfism called achondroplasia
Mendelian dominant trait
Fracture
Closed (simple) : no skin
Open (compound) : skin ✔️
Requires “ reduction” for alignment
Repair by granulation tissue
Union by callus
Consolidation by other bones
Vitamin ( D)
Rickets
3mo - 3yrs
Growing long bones
Ossification or mineralisation ✖️
Rickets diseases
- Craniotabe ( soft skull)
- Rachitic rosary at costocondral junction ( widening of ribs)
- Harrison sulcus at diaphragm ( sucked grooves ribs )
- Elongated epiphysis
- Deformity of vertebrae or pelvis
Vit C
Scurvy
Collagen fibres and matrix is impaired
Heamatoma
Widening of legs
Vertebral
By skin : spina bi fida oculta
Protrusion of meninges : meningocele
Both meninges and spine : meningo -myelocele
Vit d deficiency in adult
Osteomalacia
• phosphate and CA ↓
• alkaline phosphatase ↑
• osteoblast ↑
• thick uncalcified trabeculae
Osteoporosis
Everythung normal
Thin and small trabeculae
Porous bones
Calcium loss
Kyphosis
Osteomyelitis
Mainly in metaphysis of growing long bones
The N.A from hair pin bands in which bacteria or embolus gets trapped and infarctions occurs
Propulsion of nucleus pulposus backward , press the nerves from intervertebral foramen and causes
Herniation or disc prolapse
Temp pain in joint , with step throat , mitral walk of heart and kidney is affected
Rheumatid fever with streptococcus phyrngitis
If synovial mem thickens and inflammation occurs chronic.
Rheumatoid arthritis
Shortt hand bones
Degenerative Articular cartilage thinning and formation of peripheral osteophytes
Osteoarthritis
Long weight bearing bones
Joint me arthritis from metaphysis
Septic arthritis