Disease Flashcards

1
Q

Due to the defect in intramembranous ossification

A

Cleidocranial dysostosis
1) aplasia of clavicle
2) increased transverse dia of skull
3) retarded ossif of fontanelles

Genetic as well as environmental

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2
Q

Endochondral ossif defect

A

Cause dwarfism called achondroplasia
Mendelian dominant trait

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3
Q

Fracture

A

Closed (simple) : no skin
Open (compound) : skin ✔️
Requires “ reduction” for alignment
Repair by granulation tissue
Union by callus
Consolidation by other bones

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4
Q

Vitamin ( D)

A

Rickets
3mo - 3yrs
Growing long bones
Ossification or mineralisation ✖️

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5
Q

Rickets diseases

A
  1. Craniotabe ( soft skull)
  2. Rachitic rosary at costocondral junction ( widening of ribs)
  3. Harrison sulcus at diaphragm ( sucked grooves ribs )
  4. Elongated epiphysis
  5. Deformity of vertebrae or pelvis
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6
Q

Vit C

A

Scurvy
Collagen fibres and matrix is impaired
Heamatoma
Widening of legs

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7
Q

Vertebral

A

By skin : spina bi fida oculta
Protrusion of meninges : meningocele
Both meninges and spine : meningo -myelocele

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8
Q

Vit d deficiency in adult

A

Osteomalacia
• phosphate and CA ↓
• alkaline phosphatase ↑
• osteoblast ↑
• thick uncalcified trabeculae

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9
Q

Osteoporosis

A

Everythung normal
Thin and small trabeculae
Porous bones
Calcium loss
Kyphosis

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10
Q

Osteomyelitis

A

Mainly in metaphysis of growing long bones
The N.A from hair pin bands in which bacteria or embolus gets trapped and infarctions occurs

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11
Q

Propulsion of nucleus pulposus backward , press the nerves from intervertebral foramen and causes

A

Herniation or disc prolapse

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12
Q

Temp pain in joint , with step throat , mitral walk of heart and kidney is affected

A

Rheumatid fever with streptococcus phyrngitis

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13
Q

If synovial mem thickens and inflammation occurs chronic.

A

Rheumatoid arthritis
Shortt hand bones

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14
Q

Degenerative Articular cartilage thinning and formation of peripheral osteophytes

A

Osteoarthritis
Long weight bearing bones

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15
Q

Joint me arthritis from metaphysis

A

Septic arthritis

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16
Q

Denervation and overall cancellation of reflexes of joint liable to mechanical damage

A

Neuropathic joint
1. Leprosy ( Hansen’s disease) mycobacterium infect
2. Tabes dorsalis ( deg of nerve cells
3. Syringomyelia ( formation of cyst in spinal cord