Dirty USLME Flashcards
What are the causes of microcytic aneamia?
Iron deficiency
Sideroblastic aneamia
Thalassemias
Sometimes aneamia of chronic disease
What are the causes of aneamia with a normal MCV?
Hereditary Sphereocytosis
Paroxsysmal Nocturnal Haemoglobinuria
What are the causes of Macrocytic Aneamia?
B12 deficiency
Folate Deficiency
What is this?
Hypochromic microcytic aneamia
Low ferritin
High transferrin
Iron deficiency aneamia
What weird syndrome is associated with iron deficiency aneamia?
Plummer-vinson syndrome
What is plummer-vinson syndrome?
Oesophageal webs
Iron defiecincy
Dysphagia
what is
Increased iron
Increased Ferritin
Decreased Transferritin
Lead poisioning
Sideroblastic aneamia
What does transferrin really measure?
How badly the body wants iron
How many alpha and beta genes do you have?
4 alpha and 2 beta
What are the different types of Alpha THalassemia?
deletions
1 - normal
2 - mild aneamia
3- severe aneamia
4 - hydropsfitalis
What happens in aneamia of chronic disease?
Chronic infllammatory disorder
Hepcidin is realesed like malcom tucker to go tell the gut to stop absorbing iron and then tells ferritin to start hiding it .
low transferrin and high ferritin
What does a defect in PIGA gene cause?
Paorxsymal Nocturnal Haemoglobinuria
What are heinz bodies and bite cells characteristic off?
G6PD deficiency
What is howwell jolly bodies with jaudince characteristic offr?
Hereditory spherocytosis
Hypersegmented neutrophils?
Vitamin B12 or Folate deficiency
