Directing Acting Muscarinic Agonists Flashcards by Amberly Smith | Brainscape

Q

List drugs in class

A

Acetylcholine
Bethanechol
Pilocarpine

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Q

Acetylcholine

MOA

A

Stimulates muscarinic and nicotinic receptors

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Q

Acetylcholine

Effects

A

IV infusion similar to PNS stimulation

except: BP decreases: NO and cGMP produced by BV

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Q

Acetylcholine

Pharmacokinetics

A

Hydrolyzed by AChE

and blood psuedocholinesterase

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Q

Bethanechol

MOA

A

Non specific muscarinic agonist

highest effects: urinary bladder and GI tract

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Q

Bethanechol

Muscarinic DOC for (2)

A

Increasing GI motility

Urinary retention and inadequate emptying

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Q

Bethanechol

Pharmocokinetics

A

Resistant to AChE

quaternary ammonium ion- does not cross BBB

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Q

Pilocarpine

MOA

A

nonspecific muscarinic agonist

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