Diplopia Flashcards

1
Q

What is the most common thyroid dysfunction

A

Graves

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2
Q

What does cigarette smoking worsen

A

AMD

Graves

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3
Q

Things about Graves

A
  • TSH autoAB targeted EOMs-significant imflammation-fibroblast proliferation
  • # 1 risk of bilateral/unilateral proptosis in middle aged patient
  • BIG risk factor=cigarette smoking
  • female prediclection (8:1)
  • TSH autoAB may also attack thyroid gland-graves with thyroid dysfunction (hyper).
  • 1% have concurrent MG
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4
Q

Grading system for graves

A

NOSPECS

  • No signs to symptoms
  • Only signs, but no symptoms
  • Soft tissue involvement
  • Proptosis
  • EOM involvement with resulting diplopia; the IR is most commonly affected first, followed by the medial, superior, and LR. (IMSLO)
  • Corneal involvement
  • Sight Loss due to ONH compression (enlarged EOMs)
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5
Q

Von Graef sign

A

Upper lid lag on down gaze

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6
Q

Dalrymple sign

A

Upper lid retraction, “stare appearance”

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7
Q

EOM restrictions and Graves

A

IMSLO

-+ forced duction

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8
Q

Greates threat to vision in graves

A

ONH compression

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9
Q

Dx of graves

A

CT/MRI-enlarged EOM with sparing of tendons

Increased exophthalmometry

T3/T4/TSH blood work

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10
Q

Treatment for graves

A
  • stop smoking
  • exposure K: aggressive lubrication
  • diplopia: prism or surgery
  • ON compression: steroids, orbital decompression
  • concurrent hyperthyroidism: radioiodine, anti-thyroid meds, thyroidectomy
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11
Q

Normal exophthalmometry

A

12-22mm for whites
12-18 for asians
12-24 for AA

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12
Q

Browns syndrome

A
  • abnormal SO muscle or tendon or trochlea
  • unilateral hypotropia in primary gaze and limited elevation during adduction
  • acquired or congenital
  • chin up posture
  • (+) FD
  • Tx: prism or surgery
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13
Q

Duanes

A
  • congenital, abnornal muscles or abnormal CN3 or 6 nuclei.
  • ET in primary
  • type 1=cant abduct
  • type 2=cant adduct
  • type 3=cant adduct or abduct
  • contralateral glob retraction and narrowed palpebral fissure with adduction
  • (+) FD
  • Tx=prism or surgery
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14
Q

Ocular MG

A
  • Ach receptor autoABs
  • muscle weakness/fatigue
  • variable ptosis and diplopia worse at end of day
  • 70% have ocular findings as first presentation
  • ice pack test, Cogans lid twitch,
  • Dx=tensilon test
  • management: 10% have a thymoma, do chest CT; 5% have graves, do thyroid testing, ACH inhibitors
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15
Q

EOM entrapment

A
  • orbital floor fracture
  • entrapped IR/IO
  • restricted upgaze with diplopia and (+) FD
  • treatment: don’t blow nose for 48 hours, abx to decrease chance of infection, fresnel prism for temp diplopia, sx if persistent diplopia after 7-14 days
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16
Q

Kochers sign

A

Globe lag compared to eyelid movement on upgaze

17
Q

What drug can make ocular MG worse

A

B blockers

18
Q

Intraoribital mass

A
  • takes up space in orbit
  • unilateral painless progressive proptosis and EOM restrictions with diplopia and ON compression (unilateral optic disc edema with decreased VA, APD, and decreased color vision
19
Q

Cavernous sinus hemangioma

A

Most common benign orbital tumor in adults

20
Q

Capillary hemangioma

A

Most common benign orbital tumor in kids, Dx prior to 6m, spontaneous involution by 7y

21
Q

Rhabdomyosarcoma

A

Most common primary pediatric orbital malignancy
Rapid bone destruction tumor
Avg dx age 7

22
Q

Neuroblastoma

A

Msot common secondary pediatric orbital malignancy

-originates from abdomen, mediastinum and neck