Digoxina Flashcards

1
Q

Mecanismo de acción

A

Inhibe la bomba de Na+/K+ ATPasa.

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2
Q

Usos

A

Px con I.C. leve a moderada con sintomatología y en fibrilación auricular.

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3
Q

Rango terapéutico

A

Estrecho: 0.5-1 ng/ml

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4
Q

Beneficios

A

Disminuye las hospitalizaciones.

Aumenta en tono vagal (cronotrópico -)-

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5
Q

Factores que aumentan su toxicidad

A

Hipokalemia, hipercalcemia, hipomagnesemia, hipoxemia, anemia, acidosis, amiloidosis, edad avanzada e hipotiroidismo.

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5
Q

Factores que aumentan su toxicidad

A

Hipokalemia, hipercalcemia, hipomagnesemia, hipoxemia, anemia, acidosis, amiloidosis, edad avanzada e hipotiroidismo.

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6
Q

Factores que aumentan sus niveles sanguíneos.

A

Amiodarona, verapamilo, diltiazem, profafenona, macrólidos, itraconazol, ciclosporinas e insuficiencia renal.

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