Digestive Tract And Accessory Organs Flashcards
The mouth is
A stratified squamous epithelial mucosa-lined cavity for ingestion
The lips & cheeks are
skeletal muscle covered by skin that help to keep food between teeth when we chew
The palate forms
The roof of the mouth
Palate that aids in manipulation of food
Hard palate
Palate that rises during swallowing to close the nasopharynx
Soft palate
The tongue
- is made of skeletal muscle
- Repositions and mixes food with saliva, initiates swallowing, & aids in speech production
Taste buds are housed in
The papillae on the tongue surface
Cells types that make up the minor and major salivary glands
◦ Serous cells – produce a watery secretion (enzymes, ions, mucin)
◦ Mucous cells – produce mucus
Along with water saliva contains
◦ Electrolytes
◦ Salivary amylase & lingual lipase, mucins, lysozyme
◦ Antibodies
◦ Small amount of metabolic waste
Mastication
begins the mechanical breakdown of food & mixes food with saliva
The 20 teeth that are lost to make way for the permanent dentition are
Primary dentition (deciduous or baby teeth)
The 32 teeth, including wisdom teeth (third molars)
Permanent dentition
Incisors are used for
Cutting
Canines (cuspids) are used to
tear or pierce
Premolars (bicuspids) & molars (tricuspids) are used for
grinding
3 regions of the tooth are
◦ Enamel-covered crown
◦ Neck surrounded by gingiva (gums)
◦ Root embedded in the jawbone
Cement is
The calcified connective tissue that anchors the root to the periodontal ligaments
◦ Holds tooth in the bony socket of the jaw
Dentin is
A bone-like material that underlies the enamel & surrounds the pulp cavity (which contains blood & nerve supply)
The Oropharynx & laryngopharynx provide a
common passageway for food, fluids, & air
Food is propelled into the esophagus by
Muscular contraction within the walls
The Esophagus provides a passageway for food & fluids from
the laryngopharynx to the stomach, where it joins at the cardiac orifice
The Esophagus provides a passageway for food & fluids from
The laryngopharynx to the stomach, where it joins at the cardiac orifice
Keeps the cardiac orifice closed when food is not being swallowed
Gastroesophageal (cardiac) sphincter
2 major phases of deglutition (swallowing):
- Buccal phase – voluntary
◦ Occurs in mouth – bolus of food is
forced into oropharynx by tongue - Pharyngeal-esophageal phase – involuntary
◦ Food is squeezed through pharynx &
into esophagus
◦ Controlled by swallowing centre of
medulla & pons
Bolus being churned is
Mechanical breakdown via extra oblique layer of smooth muscle in stomach
Hydrolysis of the churned food begins
Protein digestion (via pepsin) which turns food into chyme
Folds in the stomach that wall allow stomach to expand
◦ Empty stomach – volume of ~50 ml
◦ Full capacity – 4 L Major regions include:
◦ Cardia, fundus, body, & pylorus
Rugae
Stomach’s surface epithelium of mucosa is composed of
simple columnar epithelium
◦ Surface mucous cells – produce a protective coat of alkaline mucus
Columns of secretory cells that produce gastric juice are found in
Gastric pits which extend to gastric glands
Mucous neck cells secrete
Mucus
Parietal cells secrete
- HCL to activate pepsin which denatures proteins
- intrinsic factor of glycoprotein which is required for absorption of vitamin B12 in small intestine
Chief cells secrete
◦ Pepsinogen – the inactive form of pepsin (hydrolyzes proteins in positive feedback mechanism)
◦ Gastric lipase – hydrolyzes a small portion of lipids (~15%)
G cells secrete
enteroendocrine cells that secrete gastrin
◦ Stimulates gastric secretions &
promotes movement of food along the GI tract (facilitates digestion)
H and Cl ions are secreted
Separately so they can later be assembled into HCL
Protons (H+) are secreted into stomach lumen by
proton pumps (H+-K+ ATPase powered by ATP)
Chloride ions (Cl-) move into parietal cells
via Cl-/HCO3- antiporters & diffuse into stomach lumen through Cl- channels
◦ Resulting increase in bicarbonate (HCO3-) in blood leaving the stomach – alkaline tide
In the stomach HCL secretion is stimulated by
◦ Acetylcholine (ACh) – released from parasympathetic neurons
◦ Gastrin – produced by G cells
Histamine, a paracrine released from mast cells in lamina propria enhances the effects of
ACh & gastrin
First cephalic (reflex) phase is triggered by
Aroma, taste, sight, or thought
◦preparatory phase
◦↑ saliva secretion & gastric gland acuity
The second Gastric phase is triggered by
Stretch & chemical stimuli
◦ Neural & hormonal mechanisms ↑gastric secretion & motility